BLOC1S3 and BLOC1S2

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BLOC1S3	BLOC1S2
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 3	biogenesis of lysosomal organelles complex-1, subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Transport Vesicle BLOC-1 Complex	Gamma-tubulin Complex Nucleus Mitochondrion Centrosome BLOC-1 Complex Recycling Endosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding Protein C-terminus Binding Gamma-tubulin Binding
	Biological Process	Eye Development Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Platelet Activation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Response To Drug Pigmentation Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization	Microtubule Nucleation Anterograde Axon Cargo Transport Positive Regulation Of Cell Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neuron Projection Development Melanosome Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)
Protein-Protein Interactions		2 interactors: BLOC1S1 BLOC1S2	15 interactors: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASH1
Entrez ID		388552	282991
HPRD ID		12527	12526
Ensembl ID		ENSG00000189114
Uniprot IDs		Q6QNY0	F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Dense Granule Organization Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Secretory Granule Organization Axon Cargo Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Endomembrane System Organization Synaptic Transmission Mitochondrial Outer Membrane Permeabilization Microtubule-based Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Neuron Projection Development Membrane Organization Cell-cell Signaling Positive Regulation Of Mitochondrial Membrane Permeability Neuron Development Microtubule Nucleation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Microtubule Polymerization Neuron Differentiation Cell Projection Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Microtubule Polymerization Or Depolymerization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Intracellular Transport Generation Of Neurons Neurogenesis Aerobic Respiration Mitochondrial Membrane Organization Cell Development Apoptotic Mitochondrial Changes Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Extrinsic Apoptotic Signaling Pathway Protein Polymerization	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Pigment Granule Maturation Endosome To Melanosome Transport Establishment Of Organelle Localization Intracellular Transport Cellular Pigment Accumulation Organelle Localization Microtubule-based Process Endosomal Transport Neuron Projection Development Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Neuron Development Synaptic Transmission Cellular Localization Neuron Differentiation Cell Projection Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Secretion Of Lysosomal Enzymes Cell-cell Signaling Secretion By Cell Developmental Pigmentation Generation Of Neurons Neurogenesis Golgi Vesicle Transport Platelet Dense Granule Organization Secretion Cell Development Positive Regulation Of Pigment Cell Differentiation Cytoplasmic Transport Transport Exocytosis
Tagcloud ?		apoe bin1 clu comprising correcting cr1 dataset eleven epistatic epsilon4 europe exoc3l2 fisher genotyped gwas load mark4 meta modifier near picalm replicated rs11136000 rs3818361 rs3851179 rs597668 rs744373 suggestive usa
Tagcloud (Difference) ?		apoe bin1 clu comprising correcting cr1 dataset eleven epistatic epsilon4 europe exoc3l2 fisher genotyped gwas load mark4 meta modifier near picalm replicated rs11136000 rs3818361 rs3851179 rs597668 rs744373 suggestive usa
Tagcloud (Intersection) ?