BLOC1S3 and BLOC1S1

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
HPRD (in vivo, two hybrid)

		BLOC1S3	BLOC1S1
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 3	biogenesis of lysosomal organelles complex-1, subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Transport Vesicle BLOC-1 Complex	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Eye Development Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Platelet Activation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Response To Drug Pigmentation Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Aerobic Respiration Peptidyl-lysine Acetylation Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)
Protein-Protein Interactions		2 interactors: BLOC1S1 BLOC1S2	13 interactors: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 HIST1H4A MTA1 NOTCH1 PBX2 PELP1 PTN SNAPIN
Entrez ID		388552	2647
HPRD ID		12527	03263
Ensembl ID		ENSG00000189114	ENSG00000135441
Uniprot IDs		Q6QNY0	P78537
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Dense Granule Organization Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Secretory Granule Organization Axon Cargo Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Endomembrane System Organization Synaptic Transmission Mitochondrial Outer Membrane Permeabilization Microtubule-based Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Neuron Projection Development Membrane Organization Cell-cell Signaling Positive Regulation Of Mitochondrial Membrane Permeability Neuron Development Microtubule Nucleation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Microtubule Polymerization Neuron Differentiation Cell Projection Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Microtubule Polymerization Or Depolymerization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Intracellular Transport Generation Of Neurons Neurogenesis Aerobic Respiration Mitochondrial Membrane Organization Cell Development Apoptotic Mitochondrial Changes Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Extrinsic Apoptotic Signaling Pathway Protein Polymerization	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Neuron Projection Development Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Establishment Of Organelle Localization Cellular Pigment Accumulation Neuron Differentiation Cell Projection Organization Organelle Localization Microtubule-based Process Movement Of Cell Or Subcellular Component Synaptic Transmission Generation Of Neurons Nervous System Development Neurogenesis Melanosome Transport Pigment Granule Transport Cell Development Establishment Of Melanosome Localization Melanosome Localization Establishment Of Localization In Cell Secretion Of Lysosomal Enzymes Vesicle-mediated Transport Endosomal Transport Cell-cell Signaling Secretion By Cell Developmental Pigmentation Intracellular Transport Cellular Localization Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Platelet Dense Granule Organization Wound Healing Post-Golgi Vesicle-mediated Transport Secretion Multicellular Organismal Development Positive Regulation Of Pigment Cell Differentiation
Tagcloud ?		apoe bin1 clu comprising correcting cr1 dataset eleven epistatic epsilon4 europe exoc3l2 fisher genotyped gwas load mark4 meta modifier near picalm replicated rs11136000 rs3818361 rs3851179 rs597668 rs744373 suggestive usa
Tagcloud (Difference) ?		apoe bin1 clu comprising correcting cr1 dataset eleven epistatic epsilon4 europe exoc3l2 fisher genotyped gwas load mark4 meta modifier near picalm replicated rs11136000 rs3818361 rs3851179 rs597668 rs744373 suggestive usa
Tagcloud (Intersection) ?