YPEL2 and SH2D4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YPEL2	SH2D4A
Description		yippee like 2	SH2 domain containing 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus	Cytoplasm Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Phosphatase Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) QT interval ( 24952745) Refractive error ( 32231278)	Fasting plasma glucose ( 32682390) Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)
Interacting Genes		4 interacting genes: PICK1 SH2D4A SRPK1 SRPK2	73 interacting genes: ALAS1 ARC BLOC1S2 CADPS CASK CCDC172 CCDC88B CDR2 CDR2L CEP70 CEP76 CFAP53 DBNL FCHO1 FCHSD2 FSD2 GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 GRAP2 GRB2 HCLS1 HMBOX1 HOOK2 HSF2BP IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MBD3L1 MEOX2 MORN3 MRFAP1 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PICK1 PLEKHG4 PNMA1 PRKAR1B PSTPIP1 RINT1 SH3GL1 SH3RF1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 TRIML2 TTC19 UBXN11 USHBP1 VPS52 WWOX YPEL2 YPEL3 ZBTB16 ZMYND12 ZNF655 ZNF774
Entrez ID		388403	63898
HPRD ID		15682	08340
Ensembl ID		ENSG00000175155	ENSG00000104611
Uniprot IDs		Q96QA6	Q9H788
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphorylation Spliceosomal Complex Assembly Protein Phosphorylation Negative Regulation Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Regulation Of Viral Life Cycle Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of Viral Process Regulation Of RNA Splicing Magnesium Ion Binding Protein-RNA Complex Assembly Nuclear Speck Organization Membrane Curvature Sensor Activity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphate-containing Compound Metabolic Process Negative Regulation Of Actin Nucleation Regulation Of MRNA Metabolic Process R-loop Processing Protein Serine Kinase Activity RNA Splicing Neuronal Ion Channel Clustering Dendritic Spine Maintenance Protein Modification Process Protein Serine/threonine Kinase Activity Arp2/3 Complex Binding Nuclear Speck MRNA Processing Long-term Synaptic Depression Nuclear Body Organization Sperm DNA Condensation Protein Kinase Activity Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Receptor Internalization Monoamine Transport Kinase Activity MRNA Metabolic Process 14-3-3 Protein Binding Dendritic Spine Organization Innate Immune Response Regulation Of Actin Nucleation Chromosome Negative Regulation Of Synaptic Transmission Cytosol Peptidyl-serine Phosphorylation Neuron Projection Organization Postsynapse Organization	Protein Binding Cytoplasm Cytoskeleton Organization Centrosome Microtubule Cytoskeleton Organization Cytoskeleton Vesicle-mediated Transport Microtubule-based Process Regulation Of Cytoskeleton Organization Establishment Of Localization In Cell Positive Regulation Of Cytoskeleton Organization Identical Protein Binding Cytosol Intracellular Transport Organelle Organization
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