RHOA and ROCK1

  • Number of citations of the paper that reports this interaction (PMID 8798490)
  • 41
  • Data Source:
  • HPRD (two hybrid, in vitro)

RHOA

ROCK1

Gene Name ras homolog family member A Rho-associated, coiled-coil containing protein kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 90 interactors: AKAP13 ARHGAP1 ARHGAP10 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP5 ARHGAP8 ARHGDIA ARHGDIB ARHGDIG ARHGEF1 ARHGEF11 ARHGEF12 ARHGEF18 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF4 BCR BIRC2 CAV1 CIT CNKSR1 CNTNAP1 DAAM1 DCUN1D1 DEF6 DGKQ DIAPH1 DIAPH3 DOCK7 DVL2 FAM65B FLNA GMIP GNA12 GNB2L1 HSPA1A ICMT IKBKG IKZF3 ITPR1 KCNA2 KCTD13 KTN1 MCF2 MCF2L MPRIP NET1 OPHN1 OTUB1 PDE6D PITPNM1 PKN1 PKN2 PLCG1 PLD1 PLEKHG2 PPP1R12A PRKACA PRKCA PRKCZ RABAC1 RAP1GDS1 RASGRF1 RHPN1 RHPN2 RIPK4 ROCK1 RPN2 RTKN SH3BP1 SMAD2 SMURF1 SMURF2 SPRED2 SRGAP1 TEC TGFBR1 TGM2 TNFAIP1 TRIO TRIP6 TRPC1 VAV1 VAV2 VAV3 32 interactors: ADD1 ARHGAP24 C6orf165 CASP3 CASP7 CDC25A CDC34 CRMP1 DES DPYSL2 EZR FAM124A GFAP IKBKB IRS1 ITSN2 LIMK1 LIMK2 LMO2 MAGEB4 MSN PFN2 POLR3C PPP1R12A PTK2 RDX RHOA RHOC RND3 SMAD2 TSG101 VIM
Entrez ID 387 6093
HPRD ID 01323 03414
Ensembl ID ENSG00000067560
Uniprot IDs P61586 Q9BVT0 Q13464
PDB IDs 1A2B 1CC0 1CXZ 1DPF 1FTN 1KMQ 1LB1 1OW3 1S1C 1TX4 1X86 1XCG 2RGN 3KZ1 3LW8 3LWN 3LXR 3MSX 3T06 1S1C 2ESM 2ETK 2ETR 2V55 3D9V 3NCZ 3NDM 3O0Z 3TV7 3TWJ 3V8S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1beta  a549  acetyltransferase  actinomycin  bk  bronchial  c3  cat  chloramphenicol  constitutively  cotransfection  eliminated  enhancer  enhancers  exoenzyme  hoe  immunoreactive  kappab  microg  plasmid  q63l  reporter  secreted  stimulate  stimulates  supernatants  t19n  transferase 
angiogenic  au  contributor  decay  disperse  dispersion  ecs  eliciting  gtpase  herpesvirus  hsp27  kapb  kaposi  kaposin  ks  kshv  latently  likewise  mk2  p115rhogef  pb  pbs  reprogramming  restore  rhoa  ribonucleoprotein  sarcoma  secrete  secretory 
Tagcloud (Difference) ?
1beta  a549  acetyltransferase  actinomycin  bk  bronchial  c3  cat  chloramphenicol  constitutively  cotransfection  eliminated  enhancer  enhancers  exoenzyme  hoe  immunoreactive  kappab  microg  plasmid  q63l  reporter  secreted  stimulate  stimulates  supernatants  t19n  transferase 
angiogenic  au  contributor  decay  disperse  dispersion  ecs  eliciting  gtpase  herpesvirus  hsp27  kapb  kaposi  kaposin  ks  kshv  latently  likewise  mk2  p115rhogef  pb  pbs  reprogramming  restore  ribonucleoprotein  sarcoma  secrete  secretory 
Tagcloud (Intersection) ?
rhoa