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QPRT

Description quinolinate phosphoribosyltransferase
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GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Extracellular Exosome
  • Catalytic Complex
Molecular Function
  • Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity
  • Protein Binding
  • Transferase Activity
  • Glycosyltransferase Activity
  • Pentosyltransferase Activity
  • Identical Protein Binding
Biological Process
  • NAD+ Biosynthetic Process
  • Pyridine Nucleotide Biosynthetic Process
  • NAD+ Metabolic Process
  • Quinolinate Catabolic Process
  • 'de Novo' NAD+ Biosynthetic Process From L-tryptophan
  • Quinolinate Metabolic Process
Pathways
  • Nicotinate metabolism
Drugs
  • Niacin
Diseases
GWAS
Novel Interacting Genes 2 novel interacting genes: BCKDK ETS1
Interacting Genes 9 interacting genes: ADAMTSL4 GIT2 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-8 KRTAP4-12 NOTCH2NLA SUFU
Entrez ID 23475
HPRD ID 06950
Ensembl ID ENSG00000103485
Uniprot IDs B4DDH4 H3BP73 Q15274 V9HWJ5
PDB IDs 2JBM 4KWV 4KWW 5AYX 5AYY 5AYZ
Enriched GO Terms of Interacting Partners?
  • Keratin Filament
  • Intermediate Filament
  • [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
  • Regulation Of Cellular Response To Drug
  • Positive Regulation Of Cellular Response To Drug
  • Pigment Cell Development
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