LYVE1 and AQP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LYVE1	AQP10
Description		lymphatic vessel endothelial hyaluronan receptor 1	aquaporin 10
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GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome Cell Periphery	Lipid Droplet Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Hyaluronic Acid Binding Signaling Receptor Activity Cargo Receptor Activity	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity
	Biological Process	Positive Regulation Of Cellular Extravasation Glycosaminoglycan Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Cell-matrix Adhesion Response To Wounding Anatomical Structure Morphogenesis Hyaluronan Catabolic Process	Water Transport Response To Toxic Substance Glycerol Transmembrane Transport Protein Homotetramerization Transmembrane Transport Urea Transmembrane Transport
Pathways		Hyaluronan metabolism Hyaluronan degradation	Passive transport by Aquaporins
Drugs		Hyaluronic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein levels ( 29403010)
Interacting Genes		26 interacting genes: AIG1 AQP10 CLCN7 CYSRT1 EMP3 KRT34 KRTAP10-3 KRTAP10-8 KRTAP12-3 KRTAP6-2 KRTAP9-2 NBPF19 NINJ2 NOTCH2NLA NRSN1 PDGFB PIGF SERP2 SLC30A2 SLC38A7 SLC41A2 THSD7A THSD7B UBE2J1 VEGFA YIPF6	20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B
Entrez ID		10894	89872
HPRD ID		05753	07361
Ensembl ID		ENSG00000133800	ENSG00000143595
Uniprot IDs		B2R672 Q9Y5Y7	Q96PS8
PDB IDs		8OS2 8OXD	6F7H
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Positive Regulation Of Protein Autophosphorylation Regulation Of Protein Autophosphorylation Platelet-derived Growth Factor Receptor Binding Monoatomic Cation Transmembrane Transporter Activity	Membrane Nuclear Envelope
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