LYVE1

Gene Name		lymphatic vessel endothelial hyaluronan receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Hyaluronic Acid Binding
	Biological Process	Carbohydrate Metabolic Process Transport Movement Of Cell Or Subcellular Component Cell-matrix Adhesion Signal Transduction Pathogenesis Response To Wounding Anatomical Structure Morphogenesis Glycosaminoglycan Metabolic Process Hyaluronan Metabolic Process Hyaluronan Catabolic Process Small Molecule Metabolic Process
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Hyaluronan uptake and degradation Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Hyaluronan metabolism Defective CHST6 causes MCDC1 MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS Metabolism of carbohydrates MPS VII - Sly syndrome MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: KRTAP10-3 KRTAP10-8 PDGFB VEGFA
Entrez ID		10894
HPRD ID		05753
Ensembl ID
Uniprot IDs		B2R672 F2Z296 Q9Y5Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Chemotaxis Regulation Of Protein Autophosphorylation Positive Regulation Of Kidney Development Regulation Of Blood Vessel Endothelial Cell Migration Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation Platelet Degranulation Positive Regulation Of Epithelial Cell Migration Regulation Of Endothelial Cell Proliferation Leukocyte Chemotaxis Regulation Of Endothelial Cell Migration Positive Regulation Of Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Behavior Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Chemotaxis Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cell Chemotaxis Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of ERK1 And ERK2 Cascade Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase D Signaling Metanephric Glomerular Mesangial Cell Development Metanephric Glomerular Endothelium Development Basophil Chemotaxis Positive Regulation Of MAP Kinase Activity Leukocyte Migration Morphogenesis Of A Branching Epithelium Regulation Of Cell Division Morphogenesis Of A Branching Structure Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Epithelial Cell Proliferation Regulation Of MAP Kinase Activity Response To Hypoxia Metanephric Glomerular Mesangial Cell Differentiation Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Positive Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Protein Localization To Early Endosome Negative Regulation Of Phosphatidylinositol Biosynthetic Process Paracrine Signaling Cellular Response To Mycophenolic Acid Positive Regulation Of Retinal Ganglion Cell Axon Guidance
Tagcloud ?		cd31 collects consist cyst diminish disfiguring enlarged hd hyper implicate lec lm ly294 lymphatic malformation malformations microcystic overgrowth pi3 pik3r3 podoplanin prox1 sclerotherapy sprouting stop surgically thr308 wortmannin