EPC1 and HOPX

Number of citations of the paper that reports this interaction (PubMedID 17192267)
0

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		EPC1	HOPX
Description		enhancer of polycomb 1	HOP homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body Nuclear Membrane Piccolo Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex Site Of Double-strand Break	Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding Chromatin-protein Adaptor Activity Enzyme-substrate Adaptor Activity	DNA Binding Protein Binding Histone Deacetylase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Nonhomologous End Joining Chromatin Organization DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Spermatogenesis Spermatid Development Cell Differentiation Sperm DNA Condensation Regulation Of Apoptotic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Negative Regulation Of Transcription By RNA Polymerase II Trophectodermal Cell Differentiation Bundle Of His Development Regulation Of Transcription By RNA Polymerase II Heart Development Regulation Of Heart Contraction Cell Differentiation Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Cell Differentiation Lung Alveolus Development Chaperone-mediated Protein Complex Assembly Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Gap Junction Assembly
Pathways		HATs acetylate histones Transcriptional Regulation by E2F6	Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 27863252 32888494) Sexual dysfunction (female) ( 22509378) Waist-hip index ( 34021172)	Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic sclerosis ( 30247649)
Interacting Genes		8 interacting genes: CHRM5 E2F6 HOPX KRT15 MBTD1 RINT1 SYCE1L TRIM27	10 interacting genes: BUB1B EPC1 HDAC2 HOXB9 PICK1 PTGER4 SRF TCF12 TLX3 ZSCAN1
Entrez ID		80314	84525
HPRD ID		09941	06280
Ensembl ID		ENSG00000120616	ENSG00000171476
Uniprot IDs		Q9H2F5	Q9BPY8
PDB IDs		6NFX 8QR1 8XVG 8XVT 9C57 9C62 9C6N
Enriched GO Terms of Interacting Partners?			Response To Dopamine Chromatin Sequence-specific Double-stranded DNA Binding Response To Oxygen Levels Eyelid Development In Camera-type Eye Long-term Synaptic Depression Response To Catecholamine Animal Organ Development Monoamine Transport Response To Amphetamine DNA-binding Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Synaptic Transmission Response To Cocaine DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Response To Amine Norepinephrine Secretion Catechol O-methyltransferase Activity Cellular Response To Nutrient Levels Response To Alcohol Response To Hormone Developmental Process Positive Regulation Of Male Mating Behavior Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Negative Regulation Of Eosinophil Extravasation Serum Response Element Binding Cellular Developmental Process Negative Regulation Of Cellular Component Organization Response To Decreased Oxygen Levels Cellular Response To Phosphate Starvation Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of Cell Motility Negative Regulation Of Cell Migration Protein De-2-hydroxyisobutyrylase Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of Eosinophil Migration Bronchus Cartilage Development Cis-regulatory Region Sequence-specific DNA Binding Lung Smooth Muscle Development Negative Regulation Of Locomotion Response To Alkaloid Mitotic Checkpoint Complex Meiotic Sister Chromatid Cohesion, Centromeric Habituation Mastication Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream
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