EPC1 and HOPX

Number of citations of the paper that reports this interaction (PMID 17192267)
9

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		EPC1	HOPX
Gene Name		enhancer of polycomb homolog 1 (Drosophila)	HOP homeobox
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex	Nucleus
	Molecular Function	Histone Acetyltransferase Activity	DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Trophectodermal Cell Differentiation Transcription, DNA-templated Heart Development Regulation Of Heart Contraction Histone Deacetylation Regulation Of Protein Binding Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Cell Differentiation Lung Alveolus Development Positive Regulation Of Striated Muscle Cell Differentiation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Sexual dysfunction (female) ( 22509378)
Protein-Protein Interactions		5 interactors: E2F6 HOPX KRT15 RINT1 TRIM27	7 interactors: EPC1 HDAC2 HOXB9 SRF TCF12 TLX3 ZSCAN1
Entrez ID		80314	84525
HPRD ID		09941	06280
Ensembl ID		ENSG00000120616	ENSG00000171476
Uniprot IDs		Q68DJ2 Q9H2F5	Q9BPY8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Calcium Ion Import Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Interferon-gamma Secretion Regulation Of DNA Damage Checkpoint Negative Regulation Of Viral Release From Host Cell Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Transcription From RNA Polymerase II Promoter Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Viral Transcription Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import Trophectodermal Cell Differentiation Negative Regulation Of Cellular Metabolic Process	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Eyelid Development In Camera-type Eye Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Neurogenesis Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Regulation Of Cell Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cardiac Muscle Cell Development Positive Regulation Of Neurogenesis Hippocampus Development Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Metabolic Process Contractile Actin Filament Bundle Assembly Positive Regulation Of Cell Development Nucleobase-containing Compound Metabolic Process Muscle Structure Development Limbic System Development Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cardiac Muscle Cell Differentiation Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Growth Generation Of Neurons Regulation Of Cell Differentiation Cardiocyte Differentiation Neurogenesis Regulation Of Muscle Cell Differentiation Striated Muscle Cell Development Maintenance Of Chromatin Silencing Negative Regulation Of Beta-amyloid Clearance Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Muscle Cell Development
Tagcloud ?		aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp ube3c upregulated works	absorptive anhydrase brdu bromodeoxyuridine caii carbonic cga chromogranin crypts enterocytes enteroendocrine epcam gastrin goblet iesc isomaltase mcm2 minichromosome muc2 mucin obstacle ph3 porcine reserve sim somatostatin sox9 sucrase villin
Tagcloud (Difference) ?		aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp ube3c upregulated works	absorptive anhydrase brdu bromodeoxyuridine caii carbonic cga chromogranin crypts enterocytes enteroendocrine epcam gastrin goblet iesc isomaltase mcm2 minichromosome muc2 mucin obstacle ph3 porcine reserve sim somatostatin sox9 sucrase villin
Tagcloud (Intersection) ?