KRT76 and KRT86

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT76	KRT86
Description		keratin 76	keratin 86
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Cytoskeleton Organization Epidermis Development Keratinization Pigmentation Intermediate Filament Organization Sebaceous Gland Development	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS			Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		47 interacting genes: AIRIM C1orf216 CAMK2A CCDC57 CDC37 CFAP206 DPPA3 EXOC8 FOXR2 FRS3 HGS IPO11 IQUB KIFC3 KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT75 KRT86 LCA5L LMO4 MID2 MTUS2 NFKBID POLR1C RSPH14 TNS2 TRIM23 TRIM27 TRIM54 TSGA10 WASHC1 ZNF655	45 interacting genes: CAMK2B CCDC146 CDK18 CEP57 CREB5 CYSRT1 GNE HGS HSD3B7 IL16 JOSD1 KANK2 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT76 MAPKBP1 MEOX2 MGAT5B MKRN3 NUTF2 ODF1 OIP5 OLIG3 RESF1 RTP5 SHC3 TEKT4 TSGA10IP ZNF414 ZNF655
Entrez ID		51350	3892
HPRD ID		17123	03567
Ensembl ID		ENSG00000185069	ENSG00000170442
Uniprot IDs		Q01546	A8K872 O43790
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Organelle Organization Extracellular Exosome Anatomical Structure Morphogenesis Cell Differentiation Radial Spoke Hair Cycle Protein Binding Cellular Developmental Process Cytosol Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Structural Constituent Of Cytoskeleton Regulation Of Autophagy Developmental Process Epidermis Development Negative Regulation Of Viral Transcription Exocyst Keratinization Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Positive Regulation Of Autophagy Regulation Of Viral Transcription Actin Nucleation	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Cytoskeleton Organization Epidermis Development Anatomical Structure Morphogenesis Hair Cycle Organelle Organization Cell Differentiation Extracellular Exosome Cellular Developmental Process Structural Constituent Of Cytoskeleton Tissue Development Protein Binding Developmental Process Hair Follicle Morphogenesis Cytosol Cornified Envelope Hair Cycle Process
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