KRT76 and IPO11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT76	IPO11
Description		keratin 76	importin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Cytoskeleton Organization Epidermis Development Keratinization Pigmentation Intermediate Filament Organization Sebaceous Gland Development	Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Intracellular Protein Transport Protein Transport
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Alcohol and nicotine co-dependence ( 23216389) Diffusing capacity of the lung for carbon monoxide traits ( 30049742) General risk tolerance (MTAG) ( 30643258) Interstitial lung abnormalities ( 31339356) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma selenium concentration ( 33382417) Subpleural-predominant interstitial lung abnormalities ( 31339356)
Interacting Genes		47 interacting genes: AIRIM C1orf216 CAMK2A CCDC57 CDC37 CFAP206 DPPA3 EXOC8 FOXR2 FRS3 HGS IPO11 IQUB KIFC3 KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT75 KRT86 LCA5L LMO4 MID2 MTUS2 NFKBID POLR1C RSPH14 TNS2 TRIM23 TRIM27 TRIM54 TSGA10 WASHC1 ZNF655	14 interacting genes: C1orf94 CEBPA EIF4A2 KEAP1 KRT76 NXF1 PLCD4 RAN RNF10 RPL12 TRAF2 UBE2E1 UBE2E2 UBE2E3
Entrez ID		51350	51194
HPRD ID		17123	10003
Ensembl ID		ENSG00000185069	ENSG00000086200
Uniprot IDs		Q01546	Q9UI26
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Organelle Organization Extracellular Exosome Anatomical Structure Morphogenesis Cell Differentiation Radial Spoke Hair Cycle Protein Binding Cellular Developmental Process Cytosol Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Structural Constituent Of Cytoskeleton Regulation Of Autophagy Developmental Process Epidermis Development Negative Regulation Of Viral Transcription Exocyst Keratinization Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Positive Regulation Of Autophagy Regulation Of Viral Transcription Actin Nucleation	Protein Monoubiquitination Protein Polyubiquitination Protein K48-linked Ubiquitination Ubiquitin Conjugating Enzyme Activity ISG15 Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation ISG15-protein Conjugation Post-translational Protein Modification Protein K63-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein K11-linked Ubiquitination RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA-dependent RNA Polymerase Activity Protein Metabolic Process TORC2 Complex Disassembly Macromolecule Metabolic Process Response To Vitamin B2 C/EBP Complex RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Protein Modification Process TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Protein Autoubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process RNA Export From Nucleus Nuclear Pore
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