KRT3 and BPIFA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT3	BPIFA1
Description		keratin 3	BPI fold containing family A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Lipid Binding
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization	Immune System Process Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Multicellular Organismal-level Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport
Pathways		Keratinization Formation of the cornified envelope	Antimicrobial peptides
Drugs
Diseases		Meesmann corneal dystrophy
GWAS
Interacting Genes		41 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT13 KRT14 KRT15 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765
Entrez ID		3850	51297
HPRD ID		01013	07594
Ensembl ID		ENSG00000186442	ENSG00000198183
Uniprot IDs		P12035	Q9NP55
PDB IDs			4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Supramolecular Fiber Organization Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Cytosol Extracellular Exosome Structural Constituent Of Cytoskeleton Hair Cycle Developmental Process Epidermis Development Protein Binding Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Intermediate Filament Cytoskeleton Regulation Of Microtubule Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Actin Nucleation Centriole Assembly Hydroxypyruvate Isomerase Activity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex	Protein Binding Polyubiquitin Modification-dependent Protein Binding Nucleus Myoblast Fate Commitment Pancreas Development DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin
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