KRT3 and CCDC197

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT3	CCDC197
Description		keratin 3	coiled-coil domain containing 197
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Meesmann corneal dystrophy
GWAS			Fish consumption ( 32895509)
Interacting Genes		41 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT13 KRT14 KRT15 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	19 interacting genes: BEX2 C1orf216 CCDC146 CCHCR1 CFTR CYTH4 DISC1 FMNL2 KRT3 KRT75 LCA5L NTAQ1 NXF1 RUNX1T1 SKA1 SMARCD1 TXN2 USHBP1 WASHC3
Entrez ID		3850	256369
HPRD ID		01013	12651
Ensembl ID		ENSG00000186442	ENSG00000175699
Uniprot IDs		P12035	A0A1B0GUF5 A0A1W2PPK9
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Supramolecular Fiber Organization Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Cytosol Extracellular Exosome Structural Constituent Of Cytoskeleton Hair Cycle Developmental Process Epidermis Development Protein Binding Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Intermediate Filament Cytoskeleton Regulation Of Microtubule Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Actin Nucleation Centriole Assembly Hydroxypyruvate Isomerase Activity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex
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