BPIFA1 and ALKBH4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BPIFA1	ALKBH4
Description		BPI fold containing family A member 1	alkB homolog 4, lysine demethylase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Nucleolus Cytoplasm Midbody Contractile Ring
	Molecular Function	Protein Binding Lipid Binding	Actin Binding Protein Binding Oxidoreductase Activity 2-oxoglutarate-dependent Dioxygenase Activity Demethylase Activity Broad Specificity Oxidative DNA Demethylase Activity Metal Ion Binding Dioxygenase Activity Protein Demethylase Activity DNA N6-methyladenine Demethylase Activity
	Biological Process	Immune System Process Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Multicellular Organismal-level Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport	Chromatin Organization Actomyosin Structure Organization Cleavage Furrow Ingression Demethylation Positive Regulation Of Gene Expression, Epigenetic
Pathways		Antimicrobial peptides
Drugs
Diseases
GWAS			Morning person ( 30696823)
Interacting Genes		50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765	19 interacting genes: BPIFA1 DTX2 EIF3C EP300 FAM168A GORASP2 HSF4 LCN2 MLLT1 MLLT3 MTMR6 NIF3L1 PSMA6 TCF4 TES TRAF4 TXNL4B WEE2-AS1 ZFHX3
Entrez ID		51297	54784
HPRD ID		07594	07875
Ensembl ID		ENSG00000198183	ENSG00000160993
Uniprot IDs		Q9NP55	Q9NXW9
PDB IDs		4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?		Protein Binding Polyubiquitin Modification-dependent Protein Binding Nucleus Myoblast Fate Commitment Pancreas Development DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin
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