KRT3 and KRT39

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT3	KRT39
Description		keratin 3	keratin 39
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Cytoskeleton Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Meesmann corneal dystrophy
GWAS
Interacting Genes		41 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT13 KRT14 KRT15 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	34 interacting genes: ANKS1A ARMC7 BEX2 C1orf216 CCDC196 CLCNKA FAM110A GFAP HGS IGFN1 KDM1A KLHL38 KRT1 KRT2 KRT3 KRT6B KRT74 KRT76 KRT78 KRT81 KRT83 KRT85 KRT86 LMO4 PPL PRPF18 SCNM1 SHC3 SMARCE1 TGM7 TXLNB UBASH3A VPS9D1 ZNF417
Entrez ID		3850	390792
HPRD ID		01013	13750
Ensembl ID		ENSG00000186442	ENSG00000196859
Uniprot IDs		P12035	Q6A163
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Supramolecular Fiber Organization Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Cytosol Extracellular Exosome Structural Constituent Of Cytoskeleton Hair Cycle Developmental Process Epidermis Development Protein Binding Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Intermediate Filament Cytoskeleton Regulation Of Microtubule Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Actin Nucleation Centriole Assembly Hydroxypyruvate Isomerase Activity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex	Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratinization Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Epidermis Development Organelle Organization Structural Constituent Of Cytoskeleton Cornified Envelope Tissue Development Peptide Cross-linking
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