KRT3 and C3orf62

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT3	C3orf62
Description		keratin 3	chromosome 3 open reading frame 62
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization	Spermatogenesis Cell Differentiation
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Meesmann corneal dystrophy
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depression ( 33859377) Inflammatory bowel disease ( 28067908) Red cell distribution width ( 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		41 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT13 KRT14 KRT15 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	11 interacting genes: APP BFSP2 DGCR6 HAUS1 ING5 KRT3 LMNTD2 MRFAP1 MRFAP1L1 RFPL3 TXNDC9
Entrez ID		3850	375341
HPRD ID		01013	13475
Ensembl ID		ENSG00000186442	ENSG00000188315
Uniprot IDs		P12035	Q6ZUJ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Supramolecular Fiber Organization Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Cytosol Extracellular Exosome Structural Constituent Of Cytoskeleton Hair Cycle Developmental Process Epidermis Development Protein Binding Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Intermediate Filament Cytoskeleton Regulation Of Microtubule Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Actin Nucleation Centriole Assembly Hydroxypyruvate Isomerase Activity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex
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