BPIFA1 and GCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BPIFA1	GCA
Description		BPI fold containing family A member 1	grancalcin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Lipid Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Immune System Process Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Multicellular Organismal-level Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport	Membrane Fusion
Pathways		Antimicrobial peptides	Neutrophil degranulation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765	15 interacting genes: ABHD11 ATXN1 BPIFA1 C10orf55 CALCOCO2 CSTPP1 GSTO2 LCP1 MAGEA8 PSMB4 RBFOX1 SRI TRAF1 TRAF2 YPEL3
Entrez ID		51297	25801
HPRD ID		07594	06122
Ensembl ID		ENSG00000198183	ENSG00000115271
Uniprot IDs		Q9NP55	B7Z322 H7BXD5 P28676
PDB IDs		4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L	1F4O 1F4Q 1K94 1K95
Enriched GO Terms of Interacting Partners?		Protein Binding Polyubiquitin Modification-dependent Protein Binding Nucleus Myoblast Fate Commitment Pancreas Development DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin	Thioesterase Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?