BPIFA1 and INIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BPIFA1	INIP
Description		BPI fold containing family A member 1	INTS3 and NABP interacting protein
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Nucleoplasm Site Of Double-strand Break SOSS Complex
	Molecular Function	Protein Binding Lipid Binding	Protein Binding
	Biological Process	Immune System Process Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Multicellular Organismal-level Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Response To Ionizing Radiation Mitotic G2/M Transition Checkpoint
Pathways		Antimicrobial peptides
Drugs
Diseases
GWAS			Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765	8 interacting genes: APP ARID5A BPIFA1 CFTR DGCR6 DGCR6L KRT34 RBPMS
Entrez ID		51297	58493
HPRD ID		07594	12980
Ensembl ID		ENSG00000198183	ENSG00000148153
Uniprot IDs		Q9NP55	Q9NRY2 X6R8P6
PDB IDs		4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L	4OWT 4OWW 8RBZ
Enriched GO Terms of Interacting Partners?		Protein Binding Polyubiquitin Modification-dependent Protein Binding Nucleus Myoblast Fate Commitment Pancreas Development DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin	Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Monoatomic Ion Transport Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Regulation Of Response To Calcium Ion Regulation Of Type II Interferon Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-6 Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Antibacterial Humoral Response Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Type II Interferon Production Regulation Of Monoatomic Ion Transmembrane Transport Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Multicellular Organismal-level Water Homeostasis Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Multicellular Organismal-level Chemical Homeostasis Positive Regulation Of Monoatomic Anion Transport Immune Response In Nasopharyngeal-associated Lymphoid Tissue Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Recycling Endosome Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization MRNA CDS Binding Immune Response In Gut-associated Lymphoid Tissue Response To Purine-containing Compound Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition
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