BPIFA1 and HOXB9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BPIFA1	HOXB9
Description		BPI fold containing family A member 1	homeobox B9
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Lipid Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Multicellular Organismal-level Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport	DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Cell Chemotaxis
Pathways		Antimicrobial peptides
Drugs
Diseases
GWAS			Celiac disease ( 24999842)
Interacting Genes		50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765	66 interacting genes: BPIFA1 BTG1 BTG2 CALCOCO2 CARD10 CREBBP CYSRT1 EP300 EXOSC8 FAM168B FHL5 GOLGA2 GOLGA6L9 HOPX HOXA1 HSPB2 HSPB2-C11orf52 ING4 KAT2B KRT27 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP17-1 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 LZTS2 MDFI MID2 MTUS2 MYBBP1A NBPF19 NOTCH2NLA OIP5 PCSK5 PFDN5 PHTF1 PLEKHG4 PNMA1 POLR1C RBPMS SAT1 SFMBT1 SIRT1 SPZ1 TAL1 TENM4 TET2 TNS2 TRIM27 TRIP6 ZNF408
Entrez ID		51297	3219
HPRD ID		07594	00852
Ensembl ID		ENSG00000198183	ENSG00000170689
Uniprot IDs		Q9NP55	B3KPJ1 P17482
PDB IDs		4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?		Protein Binding Polyubiquitin Modification-dependent Protein Binding Nucleus Myoblast Fate Commitment Pancreas Development DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin	Intermediate Filament Keratin Filament N-terminal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Protein Acetylation Transcription Coactivator Activity Histone Acetyltransferase Complex Cytosol N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of Cellular Response To Heat Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Diamine N-acetyltransferase Activity Acetyltransferase Activity Structural Constituent Of Skin Epidermis Identical Protein Binding Protein-lysine-acetyltransferase Activity Transcription Corepressor Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Histone Acetyltransferase Activity Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Regulation Of Transcription By Glucose Protein Binding Internal Protein Amino Acid Acetylation Structural Molecule Activity Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Epigenetic Regulation Of Gene Expression Chromatin Remodeling Pre-mRNA Intronic Binding Transcription Initiation-coupled Chromatin Remodeling
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