ACAT1 and PEX7

Number of citations of the paper that reports this interaction (PMID 22057399)
6

Data Source:
BioGRID (two hybrid)

		ACAT1	PEX7
Gene Name		acetyl-CoA acetyltransferase 1	peroxisomal biogenesis factor 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Extracellular Vesicular Exosome	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity Enzyme Binding Protein Homodimerization Activity Metal Ion Binding Coenzyme Binding	Peroxisome Matrix Targeting Signal-2 Binding Enzyme Binding Protein Homodimerization Activity
	Biological Process	Liver Development Brain Development Branched-chain Amino Acid Catabolic Process Response To Hormone Response To Organic Cyclic Compound Cellular Nitrogen Compound Metabolic Process Response To Starvation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Cellular Ketone Body Metabolic Process Ketone Body Biosynthetic Process Ketone Body Catabolic Process Protein Homooligomerization Adipose Tissue Development Metanephric Proximal Convoluted Tubule Development	Neuron Migration Endochondral Ossification Fatty Acid Beta-oxidation Peroxisome Organization Ether Lipid Biosynthetic Process Protein Import Into Peroxisome Matrix
Pathways		Ketone body metabolism Fatty acid, triacylglycerol, and ketone body metabolism Synthesis of Ketone Bodies Metabolism of lipids and lipoproteins Branched-chain amino acid catabolism Utilization of Ketone Bodies Metabolism of amino acids and derivatives
Drugs		Sulfasalazine
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AGXT PEX7	7 interactors: ACAT1 KDM1A PEX13 PEX14 PEX5 PHYH PRMT6
Entrez ID		38	5191
HPRD ID		01946	03454
Ensembl ID		ENSG00000075239	ENSG00000112357
Uniprot IDs		P24752	O00628 Q6FGN1
PDB IDs		2F2S 2IB7 2IB8 2IB9 2IBU 2IBW 2IBY
Enriched GO Terms of Interacting Partners?		Carboxylic Acid Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate Oxalic Acid Secretion L-cysteine Catabolic Process Glyoxylate Catabolic Process L-alanine Metabolic Process L-alanine Catabolic Process Oxalate Transport Pyruvate Biosynthetic Process Ether Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process Glyoxylate Metabolic Process Cysteine Metabolic Process Ether Lipid Metabolic Process Protein Import Into Peroxisome Matrix Glycine Biosynthetic Process Serine Family Amino Acid Catabolic Process Sulfur Amino Acid Catabolic Process Aldehyde Catabolic Process Glycerol Ether Metabolic Process Carboxylic Acid Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Organic Acid Metabolic Process Glycine Metabolic Process Endochondral Ossification Sulfur Amino Acid Metabolic Process Fatty Acid Beta-oxidation Peroxisome Organization Intracellular Protein Transmembrane Transport Serine Family Amino Acid Metabolic Process Acid Secretion Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation Catabolic Process Fatty Acid Catabolic Process Cellular Aldehyde Metabolic Process Dicarboxylic Acid Transport Endochondral Bone Morphogenesis Small Molecule Metabolic Process Cellular Amino Acid Catabolic Process Bone Morphogenesis Response To CAMP Pyruvate Metabolic Process Cellular Amino Acid Biosynthetic Process Cellular Lipid Catabolic Process Response To Organophosphorus Protein Import Response To Glucocorticoid	Protein Import Into Peroxisome Matrix, Docking Protein To Membrane Docking Protein Import Into Peroxisome Matrix Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Negative Regulation Of Protein Homotetramerization Lipid Modification Carboxylic Acid Catabolic Process Peroxisome Organization Protein Import Into Peroxisome Matrix, Translocation Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Negative Regulation Of Protein Homooligomerization Fatty Acid Alpha-oxidation Membrane Docking Negative Regulation Of Protein Oligomerization Cellular Lipid Catabolic Process Protein Import Regulation Of Protein Oligomerization Brain Development Lipid Catabolic Process Head Development Fatty Acid Metabolic Process Cellular Lipid Metabolic Process Central Nervous System Development Establishment Of Protein Localization To Organelle Carboxylic Acid Metabolic Process Negative Regulation Of Protein Binding Organic Acid Metabolic Process Protein Targeting Protein Oligomerization Forebrain Development Lipid Metabolic Process Cerebral Cortex Cell Migration Peroxisome Transport Along Microtubule Cholesterol Storage Protein Import Into Peroxisome Matrix, Substrate Release Regulation Of Primitive Erythrocyte Differentiation Protein Localization To Organelle Telencephalon Cell Migration Forebrain Cell Migration Negative Regulation Of Binding Monocarboxylic Acid Metabolic Process Oxidation-reduction Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Histone H3-R2 Methylation Microtubule-based Peroxisome Localization
Tagcloud ?		abeta1 acyl acyltransferase amyloidopathy autophagosome blockage blocking buildup coa converting coordinated degrade disrupt eb esters implicate k604 knock ko lysosomal microglia misfolded oligomeric phagocytic pharmacologically proteolysis proteolytic resident stimulates	aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex6 pex8 pox1 puf5 rbp rfp
Tagcloud (Difference) ?		abeta1 acyl acyltransferase amyloidopathy autophagosome blockage blocking buildup coa converting coordinated degrade disrupt eb esters implicate k604 knock ko lysosomal microglia misfolded oligomeric phagocytic pharmacologically proteolysis proteolytic resident stimulates	aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex6 pex8 pox1 puf5 rbp rfp
Tagcloud (Intersection) ?