ACAT1

Gene Name		acetyl-CoA acetyltransferase 1
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity Enzyme Binding Protein Homodimerization Activity Metal Ion Binding Coenzyme Binding
	Biological Process	Liver Development Brain Development Branched-chain Amino Acid Catabolic Process Response To Hormone Response To Organic Cyclic Compound Cellular Nitrogen Compound Metabolic Process Response To Starvation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Cellular Ketone Body Metabolic Process Ketone Body Biosynthetic Process Ketone Body Catabolic Process Protein Homooligomerization Adipose Tissue Development Metanephric Proximal Convoluted Tubule Development
Pathways		Ketone body metabolism Fatty acid, triacylglycerol, and ketone body metabolism Synthesis of Ketone Bodies Metabolism of lipids and lipoproteins Branched-chain amino acid catabolism Utilization of Ketone Bodies Metabolism of amino acids and derivatives
Drugs		Sulfasalazine
Diseases
GWAS
Protein-protein Interactions		2 interactors: AGXT PEX7
Entrez ID		38
HPRD ID		01946
Ensembl ID		ENSG00000075239
Uniprot IDs		P24752
PDB IDs		2F2S 2IB7 2IB8 2IB9 2IBU 2IBW 2IBY
Enriched GO Terms of Interacting Partners?		Carboxylic Acid Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate Oxalic Acid Secretion L-cysteine Catabolic Process Glyoxylate Catabolic Process L-alanine Metabolic Process L-alanine Catabolic Process Oxalate Transport Pyruvate Biosynthetic Process Ether Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process Glyoxylate Metabolic Process Cysteine Metabolic Process Ether Lipid Metabolic Process Protein Import Into Peroxisome Matrix Glycine Biosynthetic Process Serine Family Amino Acid Catabolic Process Sulfur Amino Acid Catabolic Process Aldehyde Catabolic Process Glycerol Ether Metabolic Process Carboxylic Acid Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Organic Acid Metabolic Process Glycine Metabolic Process Endochondral Ossification Sulfur Amino Acid Metabolic Process Fatty Acid Beta-oxidation Peroxisome Organization Intracellular Protein Transmembrane Transport Serine Family Amino Acid Metabolic Process Acid Secretion Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation Catabolic Process Fatty Acid Catabolic Process Cellular Aldehyde Metabolic Process Dicarboxylic Acid Transport Endochondral Bone Morphogenesis Small Molecule Metabolic Process Cellular Amino Acid Catabolic Process Bone Morphogenesis Response To CAMP Pyruvate Metabolic Process Cellular Amino Acid Biosynthetic Process Cellular Lipid Catabolic Process Response To Organophosphorus Protein Import Response To Glucocorticoid
Tagcloud ?		abeta1 acyl acyltransferase amyloidopathy autophagosome blockage blocking buildup coa converting coordinated degrade disrupt eb esters implicate k604 knock ko lysosomal microglia misfolded oligomeric phagocytic pharmacologically proteolysis proteolytic resident stimulates