ARF3 and GGA2

Number of citations of the paper that reports this interaction (PMID 10749927)
72

Data Source:
HPRD (two hybrid)

		ARF3	GGA2
Gene Name		ADP-ribosylation factor 3	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle
	Molecular Function	GTPase Activity GTP Binding	Protein Binding ADP-ribosylation Factor Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Small Molecule Metabolic Process	Intracellular Protein Transport Vesicle-mediated Transport
Pathways		Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 KIF23 PICK1 SLC2A4	30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18
Entrez ID		377	23062
HPRD ID		00056	09347
Ensembl ID		ENSG00000134287	ENSG00000103365
Uniprot IDs		B7ZB63 P61204	Q9UJY4
PDB IDs			1MHQ
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Amylopectin Biosynthetic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Localization Vesicle-mediated Transport Mitotic Spindle Midzone Assembly Positive Regulation Of Protein Catabolic Process Mitotic Spindle Elongation DNA Methylation Involved In Embryo Development Glucose Import Dendritic Spine Maintenance Transport Spindle Midzone Assembly Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Toxin Metabolic Process Negative Regulation Of Actin Nucleation Long Term Synaptic Depression	Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity
Tagcloud ?		abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative	addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Difference) ?		abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative	addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Intersection) ?