ARF3 and KIF23

Number of citations of the paper that reports this interaction (PubMedID 10506747)
0

Data Source:
HPRD (two hybrid, in vitro)

		ARF3	KIF23
Description		ARF GTPase 3	kinesin family member 23
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Mitochondrion Centrosome Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Focal Adhesion Midbody Mitotic Spindle Flemming Body Centralspindlin Complex
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport	Mitotic Spindle Elongation Mitotic Cytokinesis Microtubule-based Movement Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways		Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)	Mean reticulocyte volume ( 32888494) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		18 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LINC00632 LNX1 PICK1 SCYL1 SLC2A4 SNCA SUMO2	12 interacting genes: ACTA1 ARF3 CLK1 LATS2 PLK1 PPP1CB RACGAP1 RBM34 SUMO2 USP8 YWHAB YWHAG
Entrez ID		377	9493
HPRD ID		00056	05455
Ensembl ID		ENSG00000134287	ENSG00000137807
Uniprot IDs		P61204	A0A7I2V5Y5 Q02241
PDB IDs		6II6 8P50	3VHX
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Protein Transport Intracellular Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Golgi Apparatus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Cell Surface Membrane Curvature Sensor Activity Regulation Of Actin Nucleation Phospholipid Binding Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Catabolic Process Trans-Golgi Network Golgi To Plasma Membrane Transport Perinuclear Region Of Cytoplasm Presynapse Amyloid-beta Binding Establishment Of Localization In Cell Intracellular Transport Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Multicellular Organism Growth Trans-Golgi Network Membrane Small GTPase Binding Golgi Vesicle Transport Phosphatidylinositol Binding Protein Localization To Membrane Chemical Synaptic Transmission Synaptic Vesicle Vesicle-mediated Transport To The Plasma Membrane Trans-synaptic Signaling Monoamine Transport Phosphatidylinositol-4-phosphate Binding Synaptic Signaling Dendritic Spine Regulation Of Supramolecular Fiber Organization Cellular Localization Presynaptic Modulation Of Chemical Synaptic Transmission Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Retrograde Transport, Endosome To Golgi Locomotory Behavior	Mitotic Cytokinesis Cytoskeleton-dependent Cytokinesis Regulation Of Protein Localization To Nucleus Spindle Midzone Midbody Cell Division Regulation Of Protein Localization Protein Sequestering Activity Neuromedin B Receptor Binding Protein Modification Process Myosin-light-chain-phosphatase Activity Negative Regulation Of Protein Localization To Nucleus Regulation Of Metabolic Process Extracellular Exosome Regulation Of Macromolecule Metabolic Process Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Sensory Perception Of Itch Sneeze Reflex Positive Regulation Of Testosterone Secretion Positive Regulation Of Osteoclast Proliferation Positive Regulation Of Respiratory Gaseous Exchange Leydig Cell Proliferation Positive Regulation Of Protein Metabolic Process Post-translational Protein Modification Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Synaptonemal Complex Disassembly Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Regulation Of Protein Stability Intracellular Signal Transduction Golgi Inheritance Myosin Phosphatase Activity Negative Regulation Of Protein Phosphorylation Negative Regulation Of Kinase Activity Protein Kinase C Inhibitor Activity Negative Regulation Of Protein Kinase Activity Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Centralspindlin Complex Actomyosin Contractile Ring Assembly
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