CYSRT1 and GSTP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYSRT1	GSTP1
Description		cysteine rich tail 1	glutathione S-transferase pi 1
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Cytoplasm Mitochondrion Cytosol Vesicle Secretory Granule Lumen Extracellular Exosome TRAF2-GSTP1 Complex Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Identical Protein Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Fatty Acid Binding Protein Binding JUN Kinase Binding Toxic Substance Binding Transferase Activity Protein Kinase Binding Protein Serine/threonine Kinase Inhibitor Activity S-nitrosoglutathione Binding Dinitrosyl-iron Complex Binding Nitric Oxide Binding
	Biological Process	Biological Process Involved In Interaction With Symbiont Establishment Of Skin Barrier	Negative Regulation Of Transcription By RNA Polymerase II Response To Reactive Oxygen Species Negative Regulation Of Acute Inflammatory Response Lipid Metabolic Process Prostaglandin Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Central Nervous System Development Response To Toxic Substance Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Oligodendrocyte Development Animal Organ Regeneration Response To Nutrient Levels Response To Estradiol Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Superoxide Anion Generation Response To L-ascorbic Acid Common Myeloid Progenitor Cell Proliferation Nitric Oxide Storage Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Response To Amino Acid Negative Regulation Of MAPK Cascade Linoleic Acid Metabolic Process Response To Ethanol Negative Regulation Of JNK Cascade Negative Regulation Of Fibroblast Proliferation Hepoxilin Biosynthetic Process Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Leukocyte Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Smooth Muscle Cell Chemotaxis Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Glutathione conjugation Detoxification of Reactive Oxygen Species Neutrophil degranulation Paracetamol ADME
Drugs			Glutathione Troglitazone Clozapine Etacrynic acid Clomipramine (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene S-Hydroxycysteine Cibacron Blue Glutathione sulfonic acid Glutathione disulfide Deoxycholic acid Deoxycholic acid S-(4-nitrobenzyl)glutathione 2-(N-morpholino)ethanesulfonic acid S-Hexylglutathione Canfosfamide Ezatiostat Exisulind S-NONYL-CYSTEINE S-(4-BROMOBENZYL)CYSTEINE Curcumin Dinitrochlorobenzene Hypericin Curcumin sulfate
Diseases			Prostate cancer
GWAS			A body shape index ( 34021172) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		503 interacting genes: A1CF ACTMAP ACY3 ADAM12 ADAMTSL3 ADAMTSL4 ADAMTSL5 AGXT ALDH3B1 ALPP ANAPC11 ANKS1A AQP1 AREG ARHGAP33 ARHGAP9 ARID5A ASTL ATG9A ATOSB ATPAF2 ATXN7L2 AVPI1 B4GALT7 BAG3 BAG6 BAHD1 BAIAP2L1 BEX1 BEX2 BLCAP BMP7 BRME1 BSCL2 C11orf16 C11orf87 C22orf39 CACNA1A CACNA1S CARD10 CARHSP1 CATSPER1 CBLL2 CBX2 CCDC120 CCDC187 CCDC28A-AS1 CCER1 CCNK CD300LG CDKL3 CELF5 CERCAM CERK CES1 CFAP206 CFP CHCHD2 CHCHD3 CHIC2 CHRD CHRNG CLCNKA CLDN19 CLDN2 CLEC18A CNNM3 CNTF COA5 COL8A1 COMP CRCT1 CREB5 CRH CRY2 CRYBA1 CRYBA2 CSF1 CST2 CST9L CTRC CTSG CTSZ CXCL16 CYP21A2 CYP2S1 DACT2 DALRD3 DBF4B DBH DCDC2B DDX43 DLGAP2 DMRT3 DNAJA3 DNASE1L3 DOCK2 DRC4 DVL3 ECE1 ECM1 EEIG1 EFEMP1 EFEMP2 EMC7 ENKD1 EPS8L1 ERH ESR2 ETNK2 FADS6 FAM124B FAM221A FAM221B FAM83A FAM90A1 FARS2 FASLG FBXL9P FBXW5 FEZF1 FHL3 FOXD2 FOXD4L1 FOXD4L3 FOXH1 FRS3 FRZB FZD10 GARIN6 GATA2 GATA3 GATA5 GCSAM GEM GGN GLB1L2 GLP1R GLYAT GNE GNG13 GPANK1 GPATCH2L GPRIN2 GPS2 GRN GSTP1 GUCD1 HBZ HCK HDHD3 HEY2 HHEX HLX HOXA1 HOXB5 HOXB9 HOXC8 HOXC9 HR HRG HSBP1 HSD3B7 HSPA12B HSPD1 HYAL2 HYPK ICAM1 ICAM4 IL16 INCA1 INO80B INPP5D INS INTS5 IQCN IQUB ITGB2 ITGB4 ITGB5 JOSD1 KCNS2 KCTD15 KLHL38 KLK8 KPRP KRT20 KRT31 KRT33B KRT34 KRT81 KRT83 KRT85 KRT86 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-3 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 KRTAP9-2 KRTAP9-3 KRTAP9-8 KSR2 LAGE3 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LENG8 LGALS9C LMF2 LMNTD2 LMO3 LMO4 LNX1 LONRF1 LONRF3 LRFN4 LRRC41 LRRN4 LYVE1 MACROH2A1 MAPKBP1 MCRS1 MED25 MELTF MEOX2 MGAT5B MIIP MKRN3 MRPL23 MRPL40 MSRB1 MT1M MTA1 MTNR1A MXD3 MXI1 MYPOP NBPF19 NDUFA9 NDUFAF3 NECTIN2 NECTIN3 NEU2 NEU4 NKD1 NMU NOTCH2NLA NOXA1 NPBWR2 NPDC1 NPPB NR1D2 NR4A3 NSD1 NTAQ1 NTN4 NUBP2 NUFIP2 OLIG3 OR7A17 OTOS OTX1 P2RX7 PATZ1 PCSK5 PDE9A PGAP2 PGAP6 PHETA1 PHLDA1 PITX1 PITX2 PKD2 PKN1 PLA2G10 PLAC8 PLEKHN1 PLLP POU4F2 PPP1CB PPY PRF1 PRKAA2 PRKAB2 PROC PROP1 PRPF31 PRR19 PRR22 PRR30 PRR34 PRR35 PTGDS PTK7 PTPMT1 PVR QRICH1 R3HDM2 RAB3IL1 RALGDS RAMAC RAMP3 RASD1 RBM22 RBP3 RECK REM2 RGL2 RGS3 RHBG RHNO1 RNF38 RPS19BP1 RPUSD3 RSPO2 RTN4RL1 SAPCD2 SAXO1 SAXO4 SAXO5 SCARF1 SCNM1 SEMA3B SEMA4C SH3KBP1 SH3RF2 SHFL SHISA6 SLC12A4 SLC13A5 SLC23A1 SLC25A18 SLC25A48 SLC43A2 SLC5A5 SLC68A1 SLC6A20 SLIT1 SMARCC1 SMARCD1 SMARCE1 SMCP SMOC1 SMUG1 SNRPB SNRPC SNX18 SOCS7 SPATA24 SPATA3 SPATA46 SPATA8 SPEF1 SPG7 SPMIP2 SPMIP4 SPMIP6 SPMIP9 SPON1 SPPL2C SPRY1 SPTSSA SRD5A2 SSC4D STK16 TAPBPL TBX2 TBX6 TCAF1 TCEA2 TCEANC TCF7L2 TENT5B TEPSIN TFAP2D TGFB1 THAP7 TIMM22 TLE5 TM7SF2 TMEM174 TNIP1 TNIP3 TNK2 TNS4 TRAPPC14 TREX1 TRIM42 TSGA10IP TSPAN4 TTC23 TTPA TYK2 UBXN7 USP54 UTP23 VASN VENTX VGLL3 VSTM4 VWC2 VWC2L WDR25 WIF1 WNT11 WT1 YPEL3 YY1 ZBTB25 ZBTB4 ZCCHC14 ZDHHC1 ZFHX2 ZIC1 ZMYND10 ZNF124 ZNF266 ZNF319 ZNF330 ZNF34 ZNF408 ZNF414 ZNF417 ZNF419 ZNF438 ZNF439 ZNF440 ZNF441 ZNF446 ZNF497 ZNF552 ZNF575 ZNF580 ZNF581 ZNF587 ZNF648 ZNF669 ZNF683 ZNF696 ZNF764 ZNF775 ZNF786 ZNF835 ZNF837 ZNF843 ZNHIT1 ZSCAN5A	39 interacting genes: ADAMTSL4 APPBP2 CARD10 CEBPA CYSRT1 FANCC FBXO8 FHL5 HOXA1 KRT31 KRT33B KRT34 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-2 LRP2BP MAPK8 MLH1 MTUS2 NBPF19 NOTCH2NLA OGT PNO1 PRDX6 PTN RNF26 SCAF1 SH3GLB1 SUMO4 TGM1 TGM2 TRAF2 ZNF655
Entrez ID		375791	2950
HPRD ID		14696	00614
Ensembl ID		ENSG00000197191	ENSG00000084207
Uniprot IDs		A8MQ03	P09211 V9HWE9
PDB IDs			10GS 11GS 12GS 13GS 14GS 16GS 17GS 18GS 19GS 1AQV 1AQW 1AQX 1EOG 1EOH 1GSS 1KBN 1LBK 1MD3 1MD4 1PGT 1PX6 1PX7 1ZGN 20GS 22GS 2A2R 2A2S 2GSS 2J9H 2PGT 3CSH 3CSI 3CSJ 3DD3 3DGQ 3GSS 3GUS 3HJM 3HJO 3HKR 3IE3 3KM6 3KMN 3KMO 3N9J 3PGT 4GSS 4PGT 5DAK 5DAL 5DCG 5DDL 5DJL 5DJM 5GSS 5J41 5JCW 5L6X 5X79 6AP9 6GSS 6LLX 6Y1E 7BIA 7GSS 7XBA 8GSS 9GSS
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Animal Organ Morphogenesis DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Structural Constituent Of Skin Epidermis	Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Protein-glutamine Gamma-glutamyltransferase Activity
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