KCNF1 and KCNH1

Number of citations of the paper that reports this interaction (PMID 12060745)
33

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCNF1	KCNH1
Gene Name		potassium channel, voltage gated modifier subfamily F, member 1	potassium channel, voltage gated eag related subfamily H, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane	Nuclear Inner Membrane Nucleoplasm Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Delayed Rectifier Potassium Channel Activity Potassium Channel Activity	Phosphorelay Sensor Kinase Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Phosphorelay Signal Transduction System Potassium Ion Transport Synaptic Transmission Myoblast Fusion Signal Transduction By Phosphorylation Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS			Circulating vasoactive peptide levels ( 23381795)
Protein-Protein Interactions		5 interactors: KCNG3 KCNG4 KCNH1 KCNV2 OPRM1	9 interactors: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 SDCBP WDYHV1
Entrez ID		3754	3756
HPRD ID		04808	04492
Ensembl ID		ENSG00000162975
Uniprot IDs		Q9H3M0	O95259
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Cell-cell Signaling Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Transmembrane Transport Ion Transport Monovalent Inorganic Cation Transport Protein Homooligomerization Protein Oligomerization Negative Regulation Of Wnt Protein Secretion Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Transport Protein Complex Assembly Signaling Cellular Response To Morphine Cell Communication Positive Regulation Of Appetite Cellular Response To Isoquinoline Alkaloid Regulation Of Membrane Potential Negative Regulation Of CAMP-mediated Signaling Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Cytosolic Calcium Ion Concentration Peptidyl-histidine Phosphorylation Opioid Receptor Signaling Pathway Behavioral Response To Ethanol Positive Regulation Of CAMP-mediated Signaling Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Nitric Oxide Biosynthetic Process Phosphorelay Signal Transduction System Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Response To Food Cellular Response To Ammonium Ion Cellular Component Assembly Regulation Of Appetite Myoblast Fusion Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Negative Regulation Of Adenylate Cyclase Activity Regulation Of CAMP-mediated Signaling Response To Food Negative Regulation Of Lyase Activity Regulation Of Sensory Perception Of Pain Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Inflammatory Response To Antigenic Stimulus	Synaptic Transmission Regulation Of Ion Transmembrane Transport Cell-cell Signaling Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transport Monovalent Inorganic Cation Transport Protein Homooligomerization Energy Derivation By Oxidation Of Organic Compounds Metal Ion Transport Cation Transmembrane Transport Generation Of Precursor Metabolites And Energy Protein Oligomerization Cation Transport Ion Transmembrane Transport Energy Reserve Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transmembrane Transport Ion Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Component Assembly Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Peptidyl-histidine Phosphorylation Transport Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Detection Of Calcium Ion Substrate-dependent Cell Migration, Cell Extension Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Protein Complex Assembly Regulation Of Cellular Localization Phosphorelay Signal Transduction System Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Signaling Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Cell Communication Polysaccharide Catabolic Process
Tagcloud ?			1c currents eag eag1 elk erg erg1 governed heag1 herg imbalance immuno itim kcnh2 kv10 kv11 kv12 nothing phosphatases pp1 prototypes ptp ptpn6 qt shp src40 subfamilies superfamily underlie
Tagcloud (Difference) ?			1c currents eag eag1 elk erg erg1 governed heag1 herg imbalance immuno itim kcnh2 kv10 kv11 kv12 nothing phosphatases pp1 prototypes ptp ptpn6 qt shp src40 subfamilies superfamily underlie
Tagcloud (Intersection) ?