KCNF1 and KCNG3

Number of citations of the paper that reports this interaction (PubMedID 12060745)
35

Data Source:
HPRD (two hybrid)

		KCNF1	KCNG3
Description		potassium voltage-gated channel modifier subfamily F member 1	potassium voltage-gated channel modifier subfamily G member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex Ciliary Base	Cytoplasm Endoplasmic Reticulum Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Non-motile Cilium Assembly	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole	Enflurane Promethazine Miconazole
Diseases
GWAS			Body mass index ( 25673413) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Thrombosis ( 26908601)
Interacting Genes		13 interacting genes: ALOX15B CLPTM1L FARS2 KCNG3 KCNG4 KCNH1 KCNV2 MCL1 OPRM1 SERP1 SLC39A7 TCEA2 TSPO	4 interacting genes: KCNB1 KCNB2 KCNC1 KCNF1
Entrez ID		3754	170850
HPRD ID		04808	16232
Ensembl ID		ENSG00000162975	ENSG00000171126
Uniprot IDs		Q9H3M0	Q8TAE7
PDB IDs
Enriched GO Terms of Interacting Partners?		Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Monoatomic Ion Transport Monoatomic Ion Channel Complex Monoatomic Cation Transmembrane Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Potassium Ion Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Channel Activity Transmembrane Transport Potassium Ion Transport Potassium Channel Regulator Activity Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Negative Regulation Of Nitric Oxide Biosynthetic Process Action Potential Regulation Of Biological Quality Protein Homooligomerization Endocannabinoid Signaling Pathway Negative Regulation Of Corticosterone Secretion Cyclic Nucleotide Binding Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Protein Complex Oligomerization Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Regulation Of Potassium Ion Transmembrane Transport Membrane Linoleate 9S-lipoxygenase Activity Linoleate 13S-lipoxygenase Activity Arachidonate 15-lipoxygenase Activity Arachidonate 8(S)-lipoxygenase Activity Lipoxin A4 Biosynthetic Process Cannabinoid Biosynthetic Process Lipoxin Biosynthetic Process Lipoxin A4 Metabolic Process Cannabinoid Signaling Pathway Contact Inhibition Response To Vitamin B1 Regulation Of Metal Ion Transport BH Domain Binding Cellular Response To Morphine Phenylalanine-tRNA Ligase Activity Phenylalanyl-tRNA Aminoacylation Regulation Of Potassium Ion Transport Negative Regulation Of Glucocorticoid Secretion	Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Delayed Rectifier Potassium Channel Activity Monoatomic Ion Channel Complex Neuronal Cell Body Membrane Potassium Ion Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Protein Homooligomerization Potassium Channel Regulator Activity Protein Complex Oligomerization Regulation Of Membrane Potential Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Dendrite Membrane Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Transport Non-motile Cilium Assembly Neuronal Cell Body Transmembrane Transport Cellular Component Assembly Dendrite Cell Projection Protein-containing Complex Assembly Regulation Of Potassium Ion Transport Localization Within Membrane Protein-containing Complex Organization Transmembrane Transporter Binding Perikaryon Regulation Of Transport Positive Regulation Of Norepinephrine Secretion Globus Pallidus Development Gated Channel Activity Neuron Projection Membrane Regulation Of Centriole-centriole Cohesion Clustering Of Voltage-gated Potassium Channels Intracellular Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Long-term Synaptic Depression Positive Regulation Of Protein Localization To Centrosome Protein Localization To Cell Periphery Postsynaptic Membrane Proximal Dendrite Cholesterol Catabolic Process Cilium Assembly
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