KCNF1 and KCNG4

Number of citations of the paper that reports this interaction (PubMedID 12060745)
35

Data Source:
HPRD (two hybrid)

		KCNF1	KCNG4
Description		potassium voltage-gated channel modifier subfamily F member 1	potassium voltage-gated channel modifier subfamily G member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex Ciliary Base	Nucleoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Potassium Channel Regulator Activity Transmembrane Transporter Binding
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Non-motile Cilium Assembly	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole	Enflurane Promethazine Miconazole
Diseases
GWAS			Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Systolic blood pressure (baseline) ( 33603002) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		13 interacting genes: ALOX15B CLPTM1L FARS2 KCNG3 KCNG4 KCNH1 KCNV2 MCL1 OPRM1 SERP1 SLC39A7 TCEA2 TSPO	3 interacting genes: KCNB1 KCNE5 KCNF1
Entrez ID		3754	93107
HPRD ID		04808	16253
Ensembl ID		ENSG00000162975	ENSG00000168418
Uniprot IDs		Q9H3M0	Q32MC1 Q547S7 Q8TDN1
PDB IDs
Enriched GO Terms of Interacting Partners?		Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Monoatomic Ion Transport Monoatomic Ion Channel Complex Monoatomic Cation Transmembrane Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Potassium Ion Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Channel Activity Transmembrane Transport Potassium Ion Transport Potassium Channel Regulator Activity Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Negative Regulation Of Nitric Oxide Biosynthetic Process Action Potential Regulation Of Biological Quality Protein Homooligomerization Endocannabinoid Signaling Pathway Negative Regulation Of Corticosterone Secretion Cyclic Nucleotide Binding Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Protein Complex Oligomerization Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Regulation Of Potassium Ion Transmembrane Transport Membrane Linoleate 9S-lipoxygenase Activity Linoleate 13S-lipoxygenase Activity Arachidonate 15-lipoxygenase Activity Arachidonate 8(S)-lipoxygenase Activity Lipoxin A4 Biosynthetic Process Cannabinoid Biosynthetic Process Lipoxin Biosynthetic Process Lipoxin A4 Metabolic Process Cannabinoid Signaling Pathway Contact Inhibition Response To Vitamin B1 Regulation Of Metal Ion Transport BH Domain Binding Cellular Response To Morphine Phenylalanine-tRNA Ligase Activity Phenylalanyl-tRNA Aminoacylation Regulation Of Potassium Ion Transport Negative Regulation Of Glucocorticoid Secretion	Potassium Channel Regulator Activity Voltage-gated Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane Potassium Ion Transport Delayed Rectifier Potassium Channel Activity Regulation Of Membrane Potential Export Across Plasma Membrane Potassium Channel Activity Metal Ion Transport Regulation Of Potassium Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Channel Complex Transmembrane Transporter Binding Monoatomic Ion Channel Activity Monoatomic Ion Transport Positive Regulation Of Norepinephrine Secretion Protein Homooligomerization Clustering Of Voltage-gated Potassium Channels Transmembrane Transport Determination Of Pancreatic Left/right Asymmetry Protein Complex Oligomerization Cilium Assembly Negative Regulation Of Potassium Ion Export Across Plasma Membrane Determination Of Liver Left/right Asymmetry Protein-containing Complex Assembly Positive Regulation Of Long-term Synaptic Depression Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Determination Of Digestive Tract Left/right Asymmetry Cilium Organization Proximal Dendrite Protein-containing Complex Organization Atrial Cardiac Muscle Cell Action Potential Regulation Of Norepinephrine Secretion Positive Regulation Of Catecholamine Secretion Regulation Of Transport Cholinergic Synapse Neuronal Ion Channel Clustering Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Regulation Of Metal Ion Transport Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Regulation Of Potassium Ion Export Across Plasma Membrane
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