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NCR3LG1 and TSPO
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
NCR3LG1
TSPO
Description
natural killer cell cytotoxicity receptor 3 ligand 1
translocator protein
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Membrane
Mitochondrial Membrane
Extracellular Exosome
Molecular Function
Protein Binding
Receptor Ligand Activity
Androgen Binding
Protein Binding
Benzodiazepine Receptor Activity
Cholesterol Binding
Transmembrane Transporter Binding
Cholesterol Transfer Activity
Biological Process
Signal Transduction
NK T Cell Activation
Protein Targeting To Mitochondrion
Steroid Biosynthetic Process
C21-steroid Hormone Biosynthetic Process
Heme Biosynthetic Process
Monoatomic Ion Transport
Monoatomic Anion Transport
Chloride Transport
Lipid Transport
Steroid Metabolic Process
Glial Cell Migration
Response To Xenobiotic Stimulus
Response To Manganese Ion
Response To Vitamin B1
Peripheral Nervous System Axon Regeneration
Sterol Transport
Adrenal Gland Development
Negative Regulation Of Protein Ubiquitination
Regulation Of Cholesterol Transport
Response To Progesterone
Negative Regulation Of Tumor Necrosis Factor Production
Response To Testosterone
Regulation Of Cell Population Proliferation
Cholesterol Homeostasis
Positive Regulation Of Apoptotic Process
Negative Regulation Of Nitric Oxide Biosynthetic Process
Response To Pain
Behavioral Response To Pain
Response To Axon Injury
Regulation Of Steroid Biosynthetic Process
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Calcium Ion Transport
Contact Inhibition
Positive Regulation Of Glial Cell Proliferation
Negative Regulation Of Glial Cell Proliferation
Positive Regulation Of Programmed Necrotic Cell Death
Cellular Response To Lipopolysaccharide
Cellular Response To Zinc Ion
Cellular Hypotonic Response
Establishment Of Protein Localization To Mitochondrion
Maintenance Of Protein Location In Mitochondrion
Negative Regulation Of Mitophagy
Negative Regulation Of ATP Metabolic Process
Response To Acetylcholine
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of Corticosterone Secretion
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Pregnenolone biosynthesis
Drugs
Chlormezanone
Zopiclone
Diseases
GWAS
Body mass index (
26426971
)
Body mass index and systole blood pressure (pairwise) (
33619380
)
Body mass index and type 2 diabetes (pairwise) (
33619380
)
Circulating leptin levels or type 2 diabetes (
32341051
)
Metabolite levels (
23823483
)
Monocyte count (
27863252
32888494
)
Monocyte percentage of white cells (
27863252
32888494
)
White blood cell count (
32888494
)
Interacting Genes
9 interacting genes:
C14orf180
C3orf52
COL4A5
ERG28
PLPP6
STX8
TMEM14C
TMEM222
TSPO
17 interacting genes:
AMIGO1
CLEC10A
CREB3L1
DBI
FAM209A
FCER1G
ICAM3
KCNF1
LEUTX
LHFPL5
LYPD5
MEOX2
NCR3LG1
PVR
TMEM14B
TMEM9
TSPOAP1
Entrez ID
374383
706
HPRD ID
16820
15913
Ensembl ID
ENSG00000188211
ENSG00000100300
Uniprot IDs
Q68D85
O76068
P30536
PDB IDs
3PV6
3PV7
4ZSO
6YJP
Enriched GO Terms of Interacting Partners
?
Steroid Biosynthetic Process
Tetrapyrrole Biosynthetic Process
Heme Biosynthetic Process
Porphyrin-containing Compound Biosynthetic Process
Porphyrin-containing Compound Metabolic Process
Steroid Metabolic Process
Heme Metabolic Process
Sterol Biosynthetic Process
Tetrapyrrole Metabolic Process
Pigment Metabolic Process
Negative Regulation Of Corticosterone Secretion
Isoprenoid Diphosphate Phosphatase Activity
Farnesyl Diphosphate Catabolic Process
Geranylgeranyl Diphosphate Catabolic Process
Contact Inhibition
Response To Vitamin B1
Regulation Of Heme Biosynthetic Process
Geranyl Diphosphate Metabolic Process
Positive Regulation Of Neutrophil Activation
Sterol Metabolic Process
Negative Regulation Of Glucocorticoid Secretion
Detection Of Cell Density
Lipid Biosynthetic Process
Androgen Binding
Maintenance Of Protein Location In Mitochondrion
Lipid Phosphatase Activity
Regulation Of Corticosterone Secretion
Collagen Type IV Trimer
Farnesyl Diphosphate Metabolic Process
Sphingosine-1-phosphate Phosphatase Activity
Peripheral Nervous System Axon Regeneration
Membrane
Chloride Channel Inhibitor Activity
Lysophosphatidic Acid Phosphatase Activity
Mitochondrial Membrane
Positive Regulation Of Mitochondrial Depolarization
Protein Prenylation
C21-steroid Hormone Biosynthetic Process
Cellular Hypotonic Response
Benzodiazepine Receptor Activity
Response To Acetylcholine
Positive Regulation Of Programmed Necrotic Cell Death
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Endoplasmic Reticulum
Regulation Of Neutrophil Activation
Hypotonic Response
Negative Regulation Of Mitophagy
Benzodiazepine Receptor Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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