NCR3LG1 and C14orf180

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NCR3LG1	C14orf180
Description		natural killer cell cytotoxicity receptor 3 ligand 1	chromosome 14 open reading frame 180
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Receptor Ligand Activity	Protein Binding
	Biological Process	Signal Transduction NK T Cell Activation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index and systole blood pressure (pairwise) ( 33619380) Body mass index and type 2 diabetes (pairwise) ( 33619380) Circulating leptin levels or type 2 diabetes ( 32341051)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Rheumatoid arthritis ( 30891314)
Interacting Genes		9 interacting genes: C14orf180 C3orf52 COL4A5 ERG28 PLPP6 STX8 TMEM14C TMEM222 TSPO	47 interacting genes: AQP3 AQP6 ARL13B ASZ1 BIK CD74 CD79A CISD2 CLEC7A CPLX4 CYBC1 EBAG9 ERGIC3 FAM174A FAM209A GPR152 GPRC5D GPX8 HAS3 KASH5 KCNJ6 LHFPL5 LIME1 MFF MGST3 MUC1 NCR3LG1 PDZK1IP1 PPP1CB PPP1CC REEP4 SAR1A SLC10A6 SLC35H1 SLC71A2 TEX29 TIMMDC1 TM4SF19 TMEM106C TMEM14B TMEM167B TMEM207 TMEM31 TMEM51 TMEM80 VSIR ZDHHC15
Entrez ID		374383	400258
HPRD ID		16820	17383
Ensembl ID		ENSG00000188211	ENSG00000184601
Uniprot IDs		Q68D85	B4DN93 J3KNP8 Q8N912
PDB IDs		3PV6 3PV7 4ZSO 6YJP
Enriched GO Terms of Interacting Partners?		Steroid Biosynthetic Process Tetrapyrrole Biosynthetic Process Heme Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process Porphyrin-containing Compound Metabolic Process Steroid Metabolic Process Heme Metabolic Process Sterol Biosynthetic Process Tetrapyrrole Metabolic Process Pigment Metabolic Process Negative Regulation Of Corticosterone Secretion Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Contact Inhibition Response To Vitamin B1 Regulation Of Heme Biosynthetic Process Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Sterol Metabolic Process Negative Regulation Of Glucocorticoid Secretion Detection Of Cell Density Lipid Biosynthetic Process Androgen Binding Maintenance Of Protein Location In Mitochondrion Lipid Phosphatase Activity Regulation Of Corticosterone Secretion Collagen Type IV Trimer Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Peripheral Nervous System Axon Regeneration Membrane Chloride Channel Inhibitor Activity Lysophosphatidic Acid Phosphatase Activity Mitochondrial Membrane Positive Regulation Of Mitochondrial Depolarization Protein Prenylation C21-steroid Hormone Biosynthetic Process Cellular Hypotonic Response Benzodiazepine Receptor Activity Response To Acetylcholine Positive Regulation Of Programmed Necrotic Cell Death Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Endoplasmic Reticulum Regulation Of Neutrophil Activation Hypotonic Response Negative Regulation Of Mitophagy	Membrane Protein Binding B Cell Receptor Complex PTW/PP1 Phosphatase Complex
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