NCR3LG1 and C3orf52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NCR3LG1	C3orf52
Description		natural killer cell cytotoxicity receptor 3 ligand 1	chromosome 3 open reading frame 52
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding Receptor Ligand Activity	Protein Binding
	Biological Process	Signal Transduction NK T Cell Activation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index and systole blood pressure (pairwise) ( 33619380) Body mass index and type 2 diabetes (pairwise) ( 33619380) Circulating leptin levels or type 2 diabetes ( 32341051)	Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		9 interacting genes: C14orf180 C3orf52 COL4A5 ERG28 PLPP6 STX8 TMEM14C TMEM222 TSPO	74 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FKBP7 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB GPX8 HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SLC10A1 SLC10A2 SLC10A6 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 UPK2 ZNRF3
Entrez ID		374383	79669
HPRD ID		16820	08018
Ensembl ID		ENSG00000188211	ENSG00000114529
Uniprot IDs		Q68D85	Q5BVD1
PDB IDs		3PV6 3PV7 4ZSO 6YJP
Enriched GO Terms of Interacting Partners?		Steroid Biosynthetic Process Tetrapyrrole Biosynthetic Process Heme Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process Porphyrin-containing Compound Metabolic Process Steroid Metabolic Process Heme Metabolic Process Sterol Biosynthetic Process Tetrapyrrole Metabolic Process Pigment Metabolic Process Negative Regulation Of Corticosterone Secretion Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Contact Inhibition Response To Vitamin B1 Regulation Of Heme Biosynthetic Process Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Sterol Metabolic Process Negative Regulation Of Glucocorticoid Secretion Detection Of Cell Density Lipid Biosynthetic Process Androgen Binding Maintenance Of Protein Location In Mitochondrion Lipid Phosphatase Activity Regulation Of Corticosterone Secretion Collagen Type IV Trimer Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Peripheral Nervous System Axon Regeneration Membrane Chloride Channel Inhibitor Activity Lysophosphatidic Acid Phosphatase Activity Mitochondrial Membrane Positive Regulation Of Mitochondrial Depolarization Protein Prenylation C21-steroid Hormone Biosynthetic Process Cellular Hypotonic Response Benzodiazepine Receptor Activity Response To Acetylcholine Positive Regulation Of Programmed Necrotic Cell Death Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Endoplasmic Reticulum Regulation Of Neutrophil Activation Hypotonic Response Negative Regulation Of Mitophagy	Membrane Protein Binding Bile Acid:sodium Symporter Activity Plasma Membrane Glutathione Peroxidase Activity Bile Acid And Bile Salt Transport Leukotriene-C4 Synthase Activity
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