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STAT6 and ANKZF1
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
STAT6
ANKZF1
Gene Name
signal transducer and activator of transcription 6, interleukin-4 induced
ankyrin repeat and zinc finger domain containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleoplasm
Cytoplasm
Cytosol
Membrane Raft
Membrane
Molecular Function
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Signal Transducer Activity
Protein Binding
Protein Phosphatase Binding
Identical Protein Binding
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
T-helper 1 Cell Lineage Commitment
Negative Regulation Of Type 2 Immune Response
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Signal Transduction
Positive Regulation Of Type I Interferon Production
Mammary Gland Epithelial Cell Proliferation
Interleukin-4-mediated Signaling Pathway
Regulation Of Cell Proliferation
Innate Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Isotype Switching To IgE Isotypes
Mammary Gland Morphogenesis
Cellular Response To Hydrogen Peroxide
Cellular Response To Reactive Nitrogen Species
Pathways
Signaling by PDGF
Downstream signal transduction
Cytosolic sensors of pathogen-associated DNA
STING mediated induction of host immune responses
STAT6-mediated induction of chemokines
Innate Immune System
Drugs
Diseases
GWAS
Eosinophilic esophagitis (pediatric) (
20208534
)
IgE levels (
22075330
)
Protein-Protein Interactions
37 interactors:
ANKZF1
ANXA2
CEBPB
CEBPE
CEBPZ
CREBBP
DAZAP2
EEF1A1
EP300
ETS1
HIST2H3C
IFNG
IL4R
IRF4
JAK1
LITAF
NCOA1
NCOA2
NFKB1
NMI
PPARG
PRKCZ
PTPN6
RCN3
RELA
RLIM
SND1
SRC
STAT2
STAT3
TP53
TRIM24
VKORC1
WWP1
ZBTB2
ZNF407
ZNF92
7 interactors:
APP
AURKB
CA2
CTTN
DNAJB11
NRSN2
STAT6
Entrez ID
6778
55139
HPRD ID
03302
07673
Ensembl ID
ENSG00000166888
ENSG00000163516
Uniprot IDs
A8K4S9
B4DQB3
P42226
Q9H8Y5
PDB IDs
1OJ5
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Cellular Response To Organic Substance
Gene Expression
Regulation Of Gene Expression
RNA Metabolic Process
Response To Organic Substance
Positive Regulation Of Transcription, DNA-templated
Defense Response
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Response To Lipid
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Immune Response
Cellular Nitrogen Compound Metabolic Process
Regulation Of Cytokine Production
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Response To Hormone
Response To Stress
Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Immune System Process
Positive Regulation Of Cytokine Production
Response To Cytokine
Regulation Of Cellular Process
Response To Biotic Stimulus
Cellular Response To Hormone Stimulus
Cellular Metabolic Process
Innate Immune Response
Regulation Of Cell Differentiation
T-helper 1 Cell Lineage Commitment
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Dipeptide Transmembrane Transport
Regulation Of Protein Binding
Histone H3-S28 Phosphorylation
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Cellular PH Reduction
Interleukin-4-mediated Signaling Pathway
Spindle Stabilization
Regulation Of Chloride Transport
Positive Regulation Of Isotype Switching To IgE Isotypes
Collateral Sprouting
Axon Midline Choice Point Recognition
Abscission
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of Cell Cycle Process
Axon Choice Point Recognition
Mitotic Spindle Midzone Assembly
Cleavage Furrow Formation
Mitotic Spindle Elongation
T-helper Cell Lineage Commitment
Angiotensin-activated Signaling Pathway
Dendritic Spine Maintenance
Regulation Of Binding
T-helper 1 Cell Differentiation
Negative Regulation Of Cytokinesis
CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment
Neuron Remodeling
Protein Localization To Kinetochore
Positive Regulation Of Cell Cycle
Anatomical Structure Morphogenesis
Response To Abiotic Stimulus
Substrate-dependent Cell Migration, Cell Extension
Spindle Midzone Assembly
Regulation Of Developmental Growth
Negative Regulation Of B Cell Apoptotic Process
Attachment Of Spindle Microtubules To Kinetochore
Protein Localization To Chromosome, Centromeric Region
Negative Regulation Of Type 2 Immune Response
Cell Adhesion
Response To Light Stimulus
Cellular Protein Complex Assembly
Mammary Gland Epithelial Cell Proliferation
Positive Regulation Of Synaptic Transmission, GABAergic
Multicellular Organismal Development
Positive Regulation Of Bone Resorption
Cellular Response To Reactive Nitrogen Species
Histone-serine Phosphorylation
Cellular Response To Fluid Shear Stress
Positive Regulation Of Isotype Switching
Tagcloud
?
13r
13ralpha
2rgammac
4r
alternative
chains
classical
consist
consists
crucial
exist
form
forms
gammac
hand
hematopoietic
il
instead
jak1
jak3
lack
predominantly
recently
regard
signals
transduction
transmitted
tyrosine
utilized
Tagcloud (Difference)
?
13r
13ralpha
2rgammac
4r
alternative
chains
classical
consist
consists
crucial
exist
form
forms
gammac
hand
hematopoietic
il
instead
jak1
jak3
lack
predominantly
recently
regard
signals
transduction
transmitted
tyrosine
utilized
Tagcloud (Intersection)
?