SPRR3 and IVL

Number of citations of the paper that reports this interaction (PubMedID 11443109)
0

Data Source:
HPRD (in vitro)

		SPRR3	IVL
Description		small proline rich protein 3	involucrin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Extracellular Exosome	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding
	Biological Process	Epidermis Development Keratinocyte Differentiation Keratinization Wound Healing	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization
Pathways		Formation of the cornified envelope	Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Inflammatory skin disease ( 25574825)	Asthma ( 31619474) Vitamin D levels ( 26704534)
Interacting Genes		3 interacting genes: EVPL IVL LORICRIN	10 interacting genes: ACD CRK CSTA DSP EVPL KRT1 LORICRIN POT1 SPRR3 UCHL5
Entrez ID		6707	3713
HPRD ID		01652	00931
Ensembl ID		ENSG00000163209	ENSG00000163207
Uniprot IDs		Q9UBC9	P07476
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Cornified Envelope Keratinization Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Modification Process Regulation Of Antibacterial Peptide Production Regulation Of Antimicrobial Humoral Response Cell Differentiation Response To UV-B Cellular Developmental Process Desmosome Protein Metabolic Process Regulation Of Humoral Immune Response Intermediate Filament Cytoskeleton Cytoskeleton Organization Structural Constituent Of Skin Epidermis Wound Healing Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process	Peptide Cross-linking Cornified Envelope Keratinocyte Differentiation Epidermal Cell Differentiation Keratinization Epidermis Development Telomere Assembly Epithelial Cell Differentiation Shelterin Complex Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Maintenance Nuclear Telomere Cap Complex Wound Healing Telomere Capping Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Telomere Maintenance Regulation Of DNA Strand Elongation Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Organelle Organization Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Developmental Process Intermediate Filament Desmosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Structural Molecule Activity Response To Stress Negative Regulation Of Telomere Maintenance Cytoskeleton Organization Response To Wounding Protein Modification Process Regulation Of Telomere Maintenance Via Telomerase Endopeptidase Inhibitor Activity Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomere Lengthening Ciliary Neurotrophic Factor Binding Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Structural Constituent Of Skin Epidermis Positive Regulation Of DNA Metabolic Process Macromolecule Metabolic Process
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