SPRR3

Description		small proline rich protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding
	Biological Process	Epidermis Development Keratinocyte Differentiation Keratinization Wound Healing
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Inflammatory skin disease ( 25574825)
Interacting Genes		3 interacting genes: EVPL IVL LORICRIN
Entrez ID		6707
HPRD ID		01652
Ensembl ID		ENSG00000163209
Uniprot IDs		Q9UBC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Cornified Envelope Keratinization Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Modification Process Regulation Of Antibacterial Peptide Production Regulation Of Antimicrobial Humoral Response Cell Differentiation Response To UV-B Cellular Developmental Process Desmosome Protein Metabolic Process Regulation Of Humoral Immune Response Intermediate Filament Cytoskeleton Cytoskeleton Organization Structural Constituent Of Skin Epidermis Wound Healing Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process
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