FST and MEST

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FST	MEST
Gene Name		follistatin	mesoderm specific transcript
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Signal Transducer Activity Protein Binding Heparan Sulfate Proteoglycan Binding Activin Binding	Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Hematopoietic Progenitor Cell Differentiation Gamete Generation Pattern Specification Process Female Gonad Development BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development	Mesoderm Development Metabolic Process Regulation Of Lipid Storage Response To Retinoic Acid
Pathways		Antagonism of Activin by Follistatin Signaling by Activin
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: BMP5 C8orf33 FN1 INHA INHBA INHBE MEST TK1 TXN	16 interactors: APP BAG6 BLOC1S2 CD300C CEP70 CMTM3 CRELD2 DBN1 FEZ1 FST HGS ING5 KIFAP3 MPZL2 ZNF205 ZNF579
Entrez ID		10468	4232
HPRD ID		00641	06776
Ensembl ID		ENSG00000134363	ENSG00000106484
Uniprot IDs		P19883	A4D1L9 B4DQW6 Q5EB52
PDB IDs		2B0U 2P6A 3HH2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Protein Phosphorylation Hemoglobin Biosynthetic Process Negative Regulation Of Gonadotropin Secretion Negative Regulation Of B Cell Differentiation Positive Regulation Of Phosphorylation Negative Regulation Of Interferon-gamma Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Macrophage Differentiation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Hemoglobin Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Male Sex Differentiation Regulation Of MAPK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of B Cell Differentiation Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Negative Regulation Of Interferon-gamma Production Endodermal Cell Differentiation Negative Regulation Of Cytokine Biosynthetic Process Negative Regulation Of B Cell Activation Sex Differentiation Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Lymphocyte Differentiation Cell Development Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Myeloid Leukocyte Differentiation Endoderm Formation Positive Regulation Of Metabolic Process Negative Regulation Of Hormone Secretion Negative Regulation Of Immune System Process Response To Stimulus Developmental Process Ovarian Follicle Development Negative Regulation Of Transport Fetal Process Involved In Parturition Negative Regulation Of Myeloid Cell Differentiation	Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Axon Cargo Transport Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion Microtubule-based Movement Regulation Of Gene Expression Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Immune System Process Regulation Of Signaling Regulation Of Cell Proliferation Membrane Organization Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Dendrite Development Organelle Localization Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Cell Differentiation Internal Protein Amino Acid Acetylation Collateral Sprouting Axon Midline Choice Point Recognition Protein Acetylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Plus-end-directed Vesicle Transport Along Microtubule Regulation Of Cellular Process Axon Choice Point Recognition Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Signal Transduction Protein Insertion Into ER Membrane Chemotaxis Establishment Of Localization In Cell Neuron Remodeling Negative Regulation Of Activin Receptor Signaling Pathway Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Hair Follicle Development Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Vesicle Localization Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		activin anthropometric blocking consideration copyright correlate elisa eumenorrheic follicular follistatin gestation luteal menstrual nested periods permit phases postpartum preeclamptic pregnancy pregnant protected reserved rights sought subset throughout towards women	bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice
Tagcloud (Difference) ?		activin anthropometric blocking consideration copyright correlate elisa eumenorrheic follicular follistatin gestation luteal menstrual nested periods permit phases postpartum preeclamptic pregnancy pregnant protected reserved rights sought subset throughout towards women	bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice
Tagcloud (Intersection) ?