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ING2 and COPS2
Number of citations of the paper that reports this interaction (PMID
17929852
)
3
Data Source:
BioGRID
(affinity chromatography technology, pull down)
ING2
COPS2
Gene Name
inhibitor of growth family, member 2
COP9 signalosome subunit 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Sin3 Complex
CCAAT-binding Factor Complex
Cytoplasm
COP9 Signalosome
Molecular Function
DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
Protein Complex Binding
Methylated Histone Binding
Phosphatidylinositol Binding
Transcription Corepressor Activity
Signal Transducer Activity
Protein Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Male Meiosis I
Signal Transduction
Spermatogenesis
Spermatid Development
Negative Regulation Of Cell Proliferation
Chromatin Modification
Sperm Motility
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Growth
Positive Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Male Germ-line Stem Cell Asymmetric Division
Seminiferous Tubule Development
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Cellular Senescence
Regulation Of Response To DNA Damage Stimulus
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Signal Transduction
Cell Proliferation
Cullin Deneddylation
Neuron Differentiation
Skeletal Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
APP
COPS2
EP300
HIST3H3
HIST4H4
SMAD1
SMURF1
SMURF2
SUMO1
39 interactors:
COPS3
COPS4
COPS5
COPS6
COPS7A
COPS8
CSNK2A1
CSNK2B
CUL1
CUL4A
CUL5
DDB1
EP300
GFER
GPS1
HIST1H3A
HIST1H4A
ING1
ING2
IP6K1
IRF8
JUN
MAP3K10
MAPK8
NCOR1
NIF3L1
NR0B1
NR2F1
PRKD1
PSMD4
RARA
RXRA
SENP8
SIN3A
SIN3B
THRA
THRB
TP53
VDR
Entrez ID
3622
9318
HPRD ID
05021
05146
Ensembl ID
ENSG00000168556
ENSG00000166200
Uniprot IDs
Q9H160
P61201
Q59EL2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Protein Modification Process
Negative Regulation Of Gene Expression
Ubiquitin-dependent SMAD Protein Catabolic Process
BMP Signaling Pathway
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Protein Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Negative Regulation Of Biosynthetic Process
Nitrogen Compound Metabolic Process
Protein Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Binding
Striated Muscle Tissue Development
Muscle Tissue Development
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Telomere Maintenance
Histone H2B Acetylation
Cellular Metabolic Process
Gene Expression
Posttranscriptional Regulation Of Gene Expression
Signal Transduction
Regulation Of Metabolic Process
Gene Silencing
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Synaptic Growth At Neuromuscular Junction
Signaling
Defense Response
Cellular Response To Growth Factor Stimulus
Protein Deneddylation
Cullin Deneddylation
Negative Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Protein Modification By Small Protein Removal
Transcription From RNA Polymerase II Promoter
Cellular Protein Modification Process
Hormone-mediated Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Protein Metabolic Process
Signal Transduction
DNA-templated Transcription, Initiation
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Negative Regulation Of Cell Proliferation
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Signaling
Cellular Response To Steroid Hormone Stimulus
Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle
Regulation Of Protein Deacetylation
Cellular Response To Lipid
Metabolic Process
Cell Communication
Intracellular Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Cell Death
Gene Expression
Tagcloud
?
acceptor
acetyltransferase
alignment
consensus
consequently
deacetylase
dgcr8
e195a
e3
ing1
ing1b
ing3
ings
isg15
k193
ligase
marks
mislocalized
pdsm
phosphomimic
pias4
preferred
reveals
s199d
stoichiometric
sumo
sumoylation
suppressors
Tagcloud (Difference)
?
acceptor
acetyltransferase
alignment
consensus
consequently
deacetylase
dgcr8
e195a
e3
ing1
ing1b
ing3
ings
isg15
k193
ligase
marks
mislocalized
pdsm
phosphomimic
pias4
preferred
reveals
s199d
stoichiometric
sumo
sumoylation
suppressors
Tagcloud (Intersection)
?