ING2

Gene Name		inhibitor of growth family, member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Sin3 Complex CCAAT-binding Factor Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Protein Complex Binding Methylated Histone Binding Phosphatidylinositol Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Meiosis I Signal Transduction Spermatogenesis Spermatid Development Negative Regulation Of Cell Proliferation Chromatin Modification Sperm Motility Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Growth Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Male Germ-line Stem Cell Asymmetric Division Seminiferous Tubule Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cellular Senescence Regulation Of Response To DNA Damage Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: APP COPS2 EP300 HIST3H3 HIST4H4 SMAD1 SMURF1 SMURF2 SUMO1
Entrez ID		3622
HPRD ID		05021
Ensembl ID		ENSG00000168556
Uniprot IDs		Q9H160
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Protein Modification Process Negative Regulation Of Gene Expression Ubiquitin-dependent SMAD Protein Catabolic Process BMP Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Binding Striated Muscle Tissue Development Muscle Tissue Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Cell Surface Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Telomere Maintenance Histone H2B Acetylation Cellular Metabolic Process Gene Expression Posttranscriptional Regulation Of Gene Expression Signal Transduction Regulation Of Metabolic Process Gene Silencing Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Growth At Neuromuscular Junction Signaling Defense Response Cellular Response To Growth Factor Stimulus
Tagcloud ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing1 ing1b ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic pias4 preferred reveals s199d stoichiometric sumo sumoylation suppressors