ING2

Description		inhibitor of growth family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane CCAAT-binding Factor Complex Sin3-type Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Deacetylase Regulator Activity Phosphatidylinositol Binding Protein-containing Complex Binding Metal Ion Binding Histone H3K4me3 Reader Activity Histone Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response Male Meiosis I Signal Transduction Spermatogenesis Spermatid Development Flagellated Sperm Motility Negative Regulation Of Cell Migration Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of DNA-templated Transcription Male Germ-line Stem Cell Asymmetric Division Seminiferous Tubule Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Cellular Senescence Negative Regulation Of Apoptotic Signaling Pathway
Pathways		SUMOylation of transcription cofactors PI5P Regulates TP53 Acetylation
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: APP COPS2 EP300 H3-4 H4C16 SMAD1 SMURF1 SMURF2
Entrez ID		3622
HPRD ID		05021
Ensembl ID		ENSG00000168556
Uniprot IDs		B2RA15 Q9H160
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Developmental Process Protein-containing Complex Regulation Of Cell Differentiation I-SMAD Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization Growth Cone Lamellipodium Chromatin Remodeling Myeloid Cell Development Chromatin Organization Regulation Of Cell Projection Organization Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Developmental Process Protein Heterodimerization Activity Positive Regulation Of Cell Differentiation Nucleoplasm Protein Localization To Chromatin Wnt Signaling Pathway Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Projection Organization Histone Crotonyltransferase Activity Regulation Of Cellular Response To Growth Factor Stimulus Transcription By RNA Polymerase II Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of BMP Signaling Pathway Engulfment Of Target By Autophagosome SMAD Binding Non-canonical Wnt Signaling Pathway Regulation Of ATP Metabolic Process Regulation Of Multicellular Organismal Process Regulation Of MiRNA Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Purine Nucleotide Metabolic Process BMP Signaling Pathway Structural Constituent Of Chromatin Acetylcholine Receptor Activator Activity
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