RBBP7 and SALL2

Number of citations of the paper that reports this interaction (PMID 21228219)
4

Data Source:
BioGRID (enzymatic study)

		RBBP7	SALL2
Gene Name		retinoblastoma binding protein 7	spalt-like transcription factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm NuRD Complex ESC/E(Z) Complex	NuRD Complex
	Molecular Function	RNA Binding Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation Gene Expression Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Cellular Heat Acclimation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Transcription, DNA-templated Neural Tube Development
Pathways		Chromosome Maintenance HDACs deacetylate histones Chromatin organization RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Cellular Senescence HATs acetylate histones PRC2 methylates histones and DNA RMTs methylate histone arginines Chromatin modifying enzymes Nucleosome assembly Oxidative Stress Induced Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: APPL1 APPL2 BCL11B BRCA1 BRMS1 BRMS1L CHD4 CREBBP DHX30 ESR1 GATAD2B HDAC1 HDAC2 HIST3H3 ING1 LINC00152 MBD3 MBD3L2 MTA2 NR2E3 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUV39H1 TWIST1	8 interactors: ADAMTSL4 CEP76 CUL4A CUL4B DDB1 EWSR1 RBBP7 ZMIZ2
Entrez ID		5931	6297
HPRD ID		04231	03743
Ensembl ID		ENSG00000102054	ENSG00000165821
Uniprot IDs		E9PC52 Q16576 Q6FHQ0	E7EW59 Q9Y467
PDB IDs		3CFS 3CFV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Chromosome Organization Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Remodeling Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cellular Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Histone Modification Regulation Of Gene Expression Organelle Organization Macromolecule Biosynthetic Process Histone Deacetylation Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Rhythmic Process Histone H3-K9 Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Eyelid Development In Camera-type Eye Tissue Development Negative Regulation Of Histone Acetylation	UV-damage Excision Repair Histone H2A Monoubiquitination Histone H2A Ubiquitination Regulation Of Cell Cycle Process Histone Monoubiquitination Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Histone Ubiquitination Protein Monoubiquitination Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cellular Response To UV DNA Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Nucleotide-excision Repair Cellular Response To Light Stimulus Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Heat Acclimation Positive Regulation Of Mitotic Cell Cycle Cellular Protein Catabolic Process Protein Ubiquitination DNA Repair Chromatin Modification Protein Modification By Small Protein Conjugation Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Catabolic Process Response To UV Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Stress Cellular Response To Radiation Proteolysis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Granulocyte Differentiation Nitrogen Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process
Tagcloud ?		accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified	adding ap4 bioinformatic deregulated deregulation doxorubicin electrophoretic embryo evidences genotoxic half hydroxy knockin mefs necessarily neurotrophin p53er r175h r248w r249s radiosensitive repress repressed represses spalt tam tamoxifen unable wt1
Tagcloud (Difference) ?		accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified	adding ap4 bioinformatic deregulated deregulation doxorubicin electrophoretic embryo evidences genotoxic half hydroxy knockin mefs necessarily neurotrophin p53er r175h r248w r249s radiosensitive repress repressed represses spalt tam tamoxifen unable wt1
Tagcloud (Intersection) ?