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RBBP7 and DHX30
Number of citations of the paper that reports this interaction (PubMedID
17255935
)
48
Data Source:
HPRD
(in vivo)
RBBP7
DHX30
Description
RB binding protein 7, chromatin remodeling factor
DExH-box helicase 30
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytosol
NuRD Complex
NURF Complex
ESC/E(Z) Complex
Sin3-type Complex
ATPase Complex
Nucleus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Cytosol
Ribonucleoprotein Granule
Mitochondrial Nucleoid
Molecular Function
RNA Binding
Protein Binding
Histone Binding
Nucleotide Binding
G-quadruplex RNA Binding
Nucleic Acid Binding
DNA Helicase Activity
Chromatin Binding
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Replication
Chromatin Organization
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Brain Development
Negative Regulation Of Cell Growth
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cell Fate Specification
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Response To Steroid Hormone
Cellular Heat Acclimation
Negative Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Stem Cell Differentiation
Central Nervous System Development
Ribosome Biogenesis
Mitochondrial Large Ribosomal Subunit Assembly
Pathways
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
HDACs deacetylate histones
PKMTs methylate histone lysines
HATs acetylate histones
RMTs methylate histone arginines
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Deposition of new CENPA-containing nucleosomes at the centromere
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Neddylation
Transcriptional Regulation by E2F6
HCMV Early Events
Potential therapeutics for SARS
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Regulation of endogenous retroelements by KRAB-ZFP proteins
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Interacting Genes
32 interacting genes:
APPL1
APPL2
BRCA1
BRMS1
BRMS1L
BUB3
CREBBP
CRYAA
CYTOR
DDB1
DHX30
ERCC6
ESR1
H3-4
H3C1
H4C1
HDAC1
HDAC2
ING1
MBD3
MTA2
NR2E3
PRKAA2
RB1
RBBP4
RBP1
SALL2
SAP30
SIN3A
SUMO2
SUV39H1
TWIST1
23 interacting genes:
CDK9
CFTR
DHX58
DUX4
HDAC1
HDAC3
HNRNPD
HSPA13
MYBBP1A
NCOR1
NEDD4
NEIL3
NR2E3
OAS3
OGT
PRPF39
RBBP4
RBBP7
RBL1
SIN3A
SKIL
TBL3
USP7
Entrez ID
5931
22907
HPRD ID
04231
13142
Ensembl ID
ENSG00000102054
ENSG00000132153
Uniprot IDs
Q16576
Q6FHQ0
H7BXY3
Q7L2E3
PDB IDs
3CFS
3CFV
7M3X
2DB2
Enriched GO Terms of Interacting Partners
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Sin3-type Complex
Negative Regulation Of Stem Cell Population Maintenance
Chromatin Remodeling
Chromatin Organization
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Stem Cell Population Maintenance
Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Nucleoplasm
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Epigenetic Regulation Of Gene Expression
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
NuRD Complex
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Biosynthetic Process
Histone Deacetylase Complex
Regulation Of Gene Expression
Negative Regulation Of Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Fate Specification
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Rhythmic Process
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Developmental Process
Histone Deacetylase Binding
Negative Regulation Of Developmental Process
Protein-containing Complex
Heterochromatin Formation
Negative Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Nucleosomal DNA Binding
Chromatin Binding
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Cell Fate Commitment
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Cell Migration
Regulation Of Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Histone Deacetylase Complex
Negative Regulation Of Macromolecule Biosynthetic Process
Sin3-type Complex
Negative Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Rhythmic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Chromatin Organization
Positive Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Nucleoplasm
Negative Regulation Of Transcription By RNA Polymerase II
Circadian Rhythm
Nucleus
Regulation Of Stem Cell Population Maintenance
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Signal Transduction
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of RNA Metabolic Process
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Cellular Response To Stress
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein-containing Complex
Histone Deacetylase Binding
NuRD Complex
Regulation Of Gene Expression
Transcription Repressor Complex
Chromatin Remodeling
Response To Stress
Circadian Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Primary Metabolic Process
Regulation Of Cell Fate Specification
Protein Lysine Delactylase Activity
Positive Regulation Of Metabolic Process
Transcription Corepressor Activity
Regulation Of Metabolic Process
Protein Decrotonylase Activity
Histone Decrotonylase Activity
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