C1QL4 and CD53

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1QL4	CD53
Description		complement C1q like 4	CD53 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space	Immunological Synapse Plasma Membrane Cell-cell Junction Membrane Specific Granule Membrane Synapse Extracellular Exosome Anchoring Junction Tertiary Granule Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Negative Regulation Of Fat Cell Differentiation Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade	Signal Transduction Receptor Clustering T Cell Receptor Signaling Pathway Positive Regulation Of Myoblast Fusion
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: CD53 CERS4 FATE1 FNDC9 GOLM1 GPR152 IL10RA LEUTX MFF RHCG SCARA5 SGTA SGTB SLC38A1 SSMEM1 TMEM179B TMPRSS2 TRHR UBQLN2	80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1
Entrez ID		338761	963
HPRD ID		17350	01054
Ensembl ID		ENSG00000186897	ENSG00000143119
Uniprot IDs		A0A3B0INP7 Q86Z23	B4DQB5 P19397
PDB IDs			6WVG
Enriched GO Terms of Interacting Partners?		Membrane TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Identical Protein Binding Regulation Of ERAD Pathway Establishment Of Protein Localization To Organelle Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Interleukin-10 Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Thyrotropin-releasing Hormone Receptor Activity Ferritin Receptor Activity Protein Targeting	Membrane Plasma Membrane Membrane Raft Distribution Membrane Raft Localization Protein Binding Bleb Assembly Membrane Raft Polarization T Cell Activation Endomembrane System Membrane Raft Organization Endoplasmic Reticulum Membrane Defense Response To Protozoan Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
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