MACO1 and LCE1E

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MACO1	LCE1E
Description		macoilin 1	late cornified envelope 1E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Axon Rough Endoplasmic Reticulum Membrane Nuclear Membrane Cell Projection Neuron Projection Neuron Projection Terminus Synapse
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Protein Binding Identical Protein Binding
	Biological Process	Chemotaxis Brain Development Neuronal Signal Transduction	Epidermis Development Keratinization
Pathways		RHOA GTPase cycle RHOC GTPase cycle	Formation of the cornified envelope
Drugs
Diseases
GWAS		LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)	Asthma ( 31619474) Inflammatory skin disease ( 25574825)
Interacting Genes		26 interacting genes: CRCT1 HOXA1 KRTAP5-2 KRTAP5-7 LCE1A LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3D LCE3E LCE5A LINGO1 MEI4 MEOX2 NBPF19 NOTCH2NLA NR4A3 POTEB3 SMAD9 SMCP SRPK2 TMEM190 ZNF655	67 interacting genes: ALPP CATSPER1 CYSRT1 EFEMP2 FAM9A FUCA2 GRN KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MEOX2 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 PIAS2 RGS17 RGS20 RNF4 SMCP SPRY1 TGM1 TRIM42 ZCCHC7
Entrez ID		55219	353135
HPRD ID		13340	13969
Ensembl ID		ENSG00000204178	ENSG00000186226
Uniprot IDs		Q8N5G2	Q5T753
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Tissue Development Developmental Process	Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Tissue Development Cytosol Protein Binding Identical Protein Binding
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