FUCA2 and KRTAP5-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FUCA2	KRTAP5-2
Description		alpha-L-fucosidase 2	keratin associated protein 5-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome	Cytosol Intermediate Filament
	Molecular Function	Alpha-L-fucosidase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation	Keratinization
Drugs			Beta-D-Glucose Pidolic acid
Diseases
GWAS		Multiple sclerosis ( 31604244)
Interacting Genes		19 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 OGT PIN1 TNPO2 VWC2 WNT11	61 interacting genes: ADAMTSL4 AP4M1 CRCT1 CREB5 CRY2 DHRS1 DLGAP3 EMC7 FAM76B FUCA2 HOXA1 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LMNTD2 MACO1 MEOX2 MT1B NUFIP2 OPCML SLC13A5 SMCP TACSTD2 UBE2I
Entrez ID		2519	440021
HPRD ID		00649	17249
Ensembl ID		ENSG00000001036	ENSG00000205867
Uniprot IDs		Q9BTY2	Q701N4
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Intermediate Filament Tissue Development Somite Development	Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Hair Cycle Protein Binding Identical Protein Binding
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