RTP2 and STX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RTP2	STX2
Description		receptor transporter protein 2	syntaxin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Extracellular Space Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Olfactory Receptor Binding Metal Ion Binding	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Identical Protein Binding Calcium-dependent Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane	Intracellular Protein Transport Exocytosis Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly
Pathways		Expression and translocation of olfactory receptors
Drugs
Diseases
GWAS		Asthma ( 31959851) Basophil count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Skin pigmentation ( 28300201)	Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)
Interacting Genes		77 interacting genes: ABHD6 ANK1 ANKS6 AQP2 AQP6 ARL13B CD74 CD79A CISD2 CLDN7 CPLX4 CXorf66 EBP ELOVL4 ELOVL6 ELOVL7 ERGIC3 EVI2A EVI2B FAM174A FAM209A FAM210B FATE1 FFAR2 GET1 GJB1 GJB5 GPR101 GPR152 GPR42 GPX8 HIBADH HSD17B11 IFNGR2 JAGN1 KASH5 KCNJ6 KIR2DL3 LAMA4 LAPTM5 LEPROTL1 LIME1 MUC1 NDUFA7 NEMP1 PDZK1IP1 REEP4 RELL2 RNASEK SAR1A SCN3B SEC11C SGPL1 SLC10A1 SLC10A6 SLC14A1 SLC34A2 SLC35H1 SLC39A9 SLC61A1 SSMEM1 STOM STX1A STX2 TAS2R5 THAP4 TMEM267 TMEM31 TMEM35A TMEM51 TMEM52B TMEM86B TMEM92 TMPPE TMX2 UACA VMA21	65 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 SNCA STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785
Entrez ID		344892	2054
HPRD ID		12371	11816
Ensembl ID		ENSG00000198471	ENSG00000111450
Uniprot IDs		Q5QGT7	A0A994J5V9 A0A994J840 P32856
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Unsaturated Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Water Transport Bile Acid:sodium Symporter Activity Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process Transmembrane Transport Fluid Transport Very Long-chain Fatty Acid Metabolic Process Renal Water Transport	SNAP Receptor Activity SNARE Complex Organelle Localization By Membrane Tethering SNARE Binding Membrane Docking Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion Vesicle Organization Membrane Organization Organelle Localization Syntaxin Binding Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Exocytosis Exocytosis Calcium-ion Regulated Exocytosis Cellular Localization Syntaxin-1 Binding Secretion By Cell Regulated Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport In Synapse Neurotransmitter Transport Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization Intracellular Transport Protein Transport Secretion Endomembrane System Signal Release SNARE Complex Assembly Synaptic Vesicle Membrane Membrane Regulation Of Exocytosis Regulation Of Secretion By Cell Regulation Of Synaptic Vesicle Priming Regulation Of Secretion Positive Regulation Of Exocytosis Intracellular Protein Transport Vesicle Intracellular Protein Localization Synaptic Vesicle Neuronal Dense Core Vesicle Exocytosis Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission Synaptic Vesicle Priming Positive Regulation Of Calcium Ion-dependent Exocytosis
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