RTP2 and FAM174A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RTP2	FAM174A
Description		receptor transporter protein 2	family with sequence similarity 174 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Olfactory Receptor Binding Metal Ion Binding	Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane
Pathways		Expression and translocation of olfactory receptors
Drugs
Diseases
GWAS		Asthma ( 31959851) Basophil count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Skin pigmentation ( 28300201)	Heel bone mineral density ( 30598549)
Interacting Genes		77 interacting genes: ABHD6 ANK1 ANKS6 AQP2 AQP6 ARL13B CD74 CD79A CISD2 CLDN7 CPLX4 CXorf66 EBP ELOVL4 ELOVL6 ELOVL7 ERGIC3 EVI2A EVI2B FAM174A FAM209A FAM210B FATE1 FFAR2 GET1 GJB1 GJB5 GPR101 GPR152 GPR42 GPX8 HIBADH HSD17B11 IFNGR2 JAGN1 KASH5 KCNJ6 KIR2DL3 LAMA4 LAPTM5 LEPROTL1 LIME1 MUC1 NDUFA7 NEMP1 PDZK1IP1 REEP4 RELL2 RNASEK SAR1A SCN3B SEC11C SGPL1 SLC10A1 SLC10A6 SLC14A1 SLC34A2 SLC35H1 SLC39A9 SLC61A1 SSMEM1 STOM STX1A STX2 TAS2R5 THAP4 TMEM267 TMEM31 TMEM35A TMEM51 TMEM52B TMEM86B TMEM92 TMPPE TMX2 UACA VMA21	36 interacting genes: ANKRD46 ARLN BET1 BNIP1 C14orf180 CCDC167 CMTM7 DEFB127 ERG28 FKBP8 GIMAP1 GIMAP5 GOSR2 HMOX1 LCK PLLP PLPP6 RTP2 SEC22A SEC22B SERP1 SLC30A2 SMCO4 SMIM1 STX7 STX8 TMEM11 TMEM203 TMEM222 TMEM239 TMEM243 TMEM42 TMEM65 TREX1 VAMP3 VAPB
Entrez ID		344892	345757
HPRD ID		12371	18260
Ensembl ID		ENSG00000198471	ENSG00000174132
Uniprot IDs		Q5QGT7	Q8TBP5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Unsaturated Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Water Transport Bile Acid:sodium Symporter Activity Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process Transmembrane Transport Fluid Transport Very Long-chain Fatty Acid Metabolic Process Renal Water Transport	SNAP Receptor Activity Membrane SNARE Complex Endoplasmic Reticulum Membrane Membrane Fusion Endoplasmic Reticulum Membrane Organization Organelle Membrane Fusion Organelle Fusion Golgi Vesicle Transport Vesicle Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Transport Vesicle Chloride Channel Inhibitor Activity Vesicle-mediated Transport Secretory Vesicle Protein Binding Endomembrane System Establishment Of Protein Localization Vesicle Docking SNARE Binding Endoplasmic Reticulum Membrane Organization Intracellular Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cellular Localization
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