RTP2 and ELOVL6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RTP2	ELOVL6
Description		receptor transporter protein 2	ELOVL fatty acid elongase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Fatty Acid Elongase Complex Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Olfactory Receptor Binding Metal Ion Binding	Protein Binding Fatty Acid Elongase Activity Transferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Expression and translocation of olfactory receptors	Activation of gene expression by SREBF (SREBP) Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Asthma ( 31959851) Basophil count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Skin pigmentation ( 28300201)	Attention deficit hyperactivity disorder ( 20732626) Benign prostatic hyperplasia ( 30988330) Liver enzyme levels (alkaline phosphatase) ( 33972514) Obesity-related traits ( 23251661) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748)
Interacting Genes		77 interacting genes: ABHD6 ANK1 ANKS6 AQP2 AQP6 ARL13B CD74 CD79A CISD2 CLDN7 CPLX4 CXorf66 EBP ELOVL4 ELOVL6 ELOVL7 ERGIC3 EVI2A EVI2B FAM174A FAM209A FAM210B FATE1 FFAR2 GET1 GJB1 GJB5 GPR101 GPR152 GPR42 GPX8 HIBADH HSD17B11 IFNGR2 JAGN1 KASH5 KCNJ6 KIR2DL3 LAMA4 LAPTM5 LEPROTL1 LIME1 MUC1 NDUFA7 NEMP1 PDZK1IP1 REEP4 RELL2 RNASEK SAR1A SCN3B SEC11C SGPL1 SLC10A1 SLC10A6 SLC14A1 SLC34A2 SLC35H1 SLC39A9 SLC61A1 SSMEM1 STOM STX1A STX2 TAS2R5 THAP4 TMEM267 TMEM31 TMEM35A TMEM51 TMEM52B TMEM86B TMEM92 TMPPE TMX2 UACA VMA21	3 interacting genes: HMOX1 LCP2 RTP2
Entrez ID		344892	79071
HPRD ID		12371	13269
Ensembl ID		ENSG00000198471	ENSG00000170522
Uniprot IDs		Q5QGT7	Q9H5J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Unsaturated Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Water Transport Bile Acid:sodium Symporter Activity Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process Transmembrane Transport Fluid Transport Very Long-chain Fatty Acid Metabolic Process Renal Water Transport	Heme Oxidation Smooth Muscle Hyperplasia Heme Oxygenase (decyclizing) Activity Wound Healing Involved In Inflammatory Response TCR Signalosome Cellular Response To Cisplatin Olfactory Receptor Binding Response To Cisplatin Smooth Muscle Adaptation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Porphyrin-containing Compound Catabolic Process Erythrocyte Homeostasis Heme Catabolic Process Mast Cell Activation Negative Regulation Of Ferroptosis Low-density Lipoprotein Particle Clearance Regulation Of Ferroptosis Cellular Response To Arsenic-containing Substance Cellular Response To Cadmium Ion Positive Regulation Of Epithelial Cell Apoptotic Process Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Multicellular Organismal-level Iron Ion Homeostasis Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Plasma Lipoprotein Particle Clearance Response To Arsenic-containing Substance Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Myeloid Cell Homeostasis Endothelial Cell Proliferation Negative Regulation Of Macroautophagy Heme Metabolic Process Plasma Membrane Raft
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