MSGN1 and MYF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSGN1	MYF5
Description		mesogenin 1	myogenic factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding
	Biological Process	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Cartilage Condensation Ossification Somitogenesis Regulation Of Cell-matrix Adhesion Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Skeletal Muscle Tissue Development Tissue Development Cell Differentiation Extracellular Matrix Organization Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Camera-type Eye Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Muscle Organ Morphogenesis Embryonic Skeletal System Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Muscle Tissue Morphogenesis
Pathways		Formation of paraxial mesoderm Somitogenesis	Myogenesis Myogenesis TGFBR3 expression
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)
Interacting Genes		28 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT	34 interacting genes: ANKRD11 AQP1 C14orf119 CALM1 CALM2 CALM3 CCDC13 CHIC2 CSNK2A1 CSNK2A2 ENKD1 FAM124B FIGLA ID1 ID2 ID3 ITGB4 MDFI MSGN1 NHLH2 PACRGL PIN1 RARG SCX SGF29 SNAPC5 TCEANC TCF3 TLE5 ZNF250 ZNF417 ZNF575 ZNF587 ZNF835
Entrez ID		343930	4617
HPRD ID			01168
Ensembl ID		ENSG00000151379	ENSG00000111049
Uniprot IDs		A6NI15	P13349
PDB IDs			7Z5I 7Z5K
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Transcription Regulator Inhibitor Activity Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Dopaminergic Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity	Regulation Of Transcription By RNA Polymerase II Protein Dimerization Activity Nucleus Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane BHLH Transcription Factor Binding Regulation Of RNA Metabolic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transcription Regulator Inhibitor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Titin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Detection Of Calcium Ion Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Animal Organ Morphogenesis Calyx Of Held Protein Kinase CK2 Complex Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol Regulation Of Cell Division Regulation Of Cytokinesis Myelin Sheath DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Primary Metabolic Process Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Cell Cycle Process Positive Regulation Of Sequestering Of Calcium Ion Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Negative Regulation Of Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Transcription Regulator Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression
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