MYF5 and ID3

Number of citations of the paper that reports this interaction (PMID 9242638)
48

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		MYF5	ID3
Gene Name		myogenic factor 5	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity E-box Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Dimerization Activity
	Biological Process	Cartilage Condensation Ossification Somitogenesis Regulation Of Cell-matrix Adhesion Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Muscle Organ Development Skeletal Muscle Tissue Development Extracellular Matrix Organization Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Camera-type Eye Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Muscle Tissue Morphogenesis Positive Regulation Of Myoblast Fusion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Regulation Of DNA Replication Transcription, DNA-templated Multicellular Organismal Development Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Response To Wounding Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CALM1 CALM2 CALM3 CSNK2A1 CSNK2A2 ELSPBP1 ID1 ID2 ID3 MDFI TCF3	36 interactors: ADD1 ATF3 CBFA2T2 CDK2 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		4617	3399
HPRD ID		01168	02608
Ensembl ID		ENSG00000111049	ENSG00000117318
Uniprot IDs		P13349	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Cycle Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Regulation Of Cell Division Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity System Development Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Nitric-oxide Synthase Activity Response To Mineralocorticoid Substantia Nigra Development Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Transporter Activity Negative Regulation Of DNA Binding Negative Regulation Of Calcium Ion Transport Multicellular Organismal Development	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Muscle Structure Development Skeletal Muscle Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Fiber Development Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Fate Commitment Negative Regulation Of Transcription From RNA Polymerase II Promoter Striated Muscle Tissue Development Multicellular Organismal Development Muscle Cell Differentiation Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Organ Development
Tagcloud ?		blastula distinguished ectoderm ectopic embryo explants lie mef2 mef2a mef2d mesoderm myod myogenesis myogenic myosin neither pole precedes presumptive reciprocal rsrf skeletal sl1 sl2 somitic tailbud xenopus xmlc2 zygotic	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Difference) ?		blastula distinguished ectoderm ectopic embryo explants lie mef2 mef2a mef2d mesoderm myod myogenesis myogenic myosin neither pole precedes presumptive reciprocal rsrf skeletal sl1 sl2 somitic tailbud xenopus xmlc2 zygotic	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Intersection) ?