MSGN1 and ID1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSGN1	ID1
Description		mesogenin 1	inhibitor of DNA binding 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding Protein Dimerization Activity Transcription Regulator Inhibitor Activity
	Biological Process	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Endothelial Cell Morphogenesis Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Heart Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Neuron Differentiation BMP Signaling Pathway Protein Destabilization Collagen Metabolic Process Regulation Of MAPK Cascade Negative Regulation Of DNA-binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Osteoblast Differentiation Regulation Of Angiogenesis Negative Regulation Of DNA-templated Transcription Response To Antibiotic Rhythmic Process Blood Vessel Morphogenesis Lung Morphogenesis Lung Vasculature Development Endothelial Cell Apoptotic Process Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		Formation of paraxial mesoderm Somitogenesis	Oncogene Induced Senescence NGF-stimulated transcription Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)	Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		28 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT	26 interacting genes: APPL1 ASCL3 CASK COPB1 DNMT3L ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MSGN1 MYF5 MYF6 MYOD1 MYOG PSMD4 RNF4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4 TRIM55 TRIM63 UBC
Entrez ID		343930	3397
HPRD ID			08980
Ensembl ID		ENSG00000151379	ENSG00000125968
Uniprot IDs		A6NI15	P41134
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Transcription Regulator Inhibitor Activity Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Dopaminergic Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity	Positive Regulation Of Transcription By RNA Polymerase II E-box Binding Protein Dimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Macromolecule Metabolic Process DNA Binding Chromatin Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Muscle Cell Fate Commitment Positive Regulation Of Metabolic Process Cell Fate Commitment Sequence-specific Double-stranded DNA Binding Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulator Complex Regulation Of Skeletal Muscle Tissue Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Anterior/posterior Pattern Specification Regulation Of Striated Muscle Tissue Development Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Muscle Organ Development Regulation Of Myotube Differentiation Positive Regulation Of Myoblast Differentiation Regulation Of Metabolic Process Somitogenesis Animal Organ Development Cell Differentiation Regulation Of Macromolecule Metabolic Process Tissue Regeneration Segmentation Muscle Organ Development
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