MSGN1 and FERD3L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSGN1	FERD3L
Description		mesogenin 1	Fer3 like bHLH transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Developmental Process Floor Plate Development Negative Regulation Of DNA-templated Transcription Cell Development Regulation Of Neurogenesis Regulation Of Dopaminergic Neuron Differentiation
Pathways		Formation of paraxial mesoderm Somitogenesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)	Allergic rhinitis ( 25085501) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549) Height ( 31562340) Obesity-related traits ( 23251661) Refractive error ( 32231278) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		28 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT	8 interacting genes: CTNNA3 FAM9B MAGEB4 MSGN1 SGTA TCF3 TMBIM6 TWIST2
Entrez ID		343930	222894
HPRD ID			16890
Ensembl ID		ENSG00000151379	ENSG00000146618
Uniprot IDs		A6NI15	Q96RJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Transcription Regulator Inhibitor Activity Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Dopaminergic Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity	Protein Dimerization Activity Negative Regulation Of Response To Endoplasmic Reticulum Stress
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