MSGN1 and DNALI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSGN1	DNALI1
Description		mesogenin 1	dynein axonemal light intermediate chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytoplasm Cilium Axoneme Microtubule Cytoskeleton Filopodium Dynein Complex Motile Cilium Sperm Flagellum Cell Projection Intercellular Bridge Mitotic Spindle Ciliary Base 9+2 Motile Cilium Dynein Axonemal Particle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding Dynein Heavy Chain Binding
	Biological Process	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Sperm Flagellum Assembly
Pathways		Formation of paraxial mesoderm Somitogenesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)	Axial length ( 24144296) Eyebrow thickness ( 26926045) Intraocular pressure ( 29617998)
Interacting Genes		28 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT	7 interacting genes: ABCF3 APP EPS8 HTT MSGN1 PRMT6 SIAH1
Entrez ID		343930	7802
HPRD ID			03681
Ensembl ID		ENSG00000151379	ENSG00000163879
Uniprot IDs		A6NI15	A0A499FIY3 O14645
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Transcription Regulator Inhibitor Activity Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Dopaminergic Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity	Gap Junction Channel Activity Connexin Complex Amyloid Fibril Formation Gap Junction Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Destabilization Histone H2AR3 Methyltransferase Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Early Endosome Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Labyrinthine Layer Morphogenesis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of CAMKK-AMPK Signaling Cascade Histone H3R2 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Cone Growth Factor Receptor Binding Main Axon Chromatin Binding Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Supramolecular Fiber Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of CAMKK-AMPK Signaling Cascade Positive Regulation Of Aggrephagy
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