DEUP1 and KRT28

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DEUP1	KRT28
Description		deuterosome assembly protein 1	keratin 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Deuterosome	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Centriole Replication Cell Projection Organization De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872) Glucose homeostasis traits ( 25524916)
Interacting Genes		44 interacting genes: AMPH ARL16 BRMS1L CCDC187 CCDC85B CCHCR1 CEP57 DGCR6 DGCR6L DTNB ESRRG EXOC5 FAM50B FBF1 GEM GOLGA2 HAUS8 HGS IFIT3 ING5 KCTD9 KIFC3 KRT15 KRT28 KRT3 LNX1 NTAQ1 PIAS2 PPP1R13B RUNX1T1 SKIL SUMO1 TBC1D22B TFPT TRIM54 TXLNA TXLNB USHBP1 ZFHX3 ZNF148 ZNF460 ZNF572 ZNF655 ZNF835	23 interacting genes: ABI3 CCDC196 DEUP1 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT76 KRT79 KRT8 KRT80 KRT81 KRT86 NUP58 UCHL5 USHBP1 WASHC1
Entrez ID		159989	162605
HPRD ID		08689	17245
Ensembl ID		ENSG00000165325	ENSG00000173908
Uniprot IDs		E9PLX9 Q05D60	Q7Z3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Binding Keratin Filament	Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Extracellular Exosome Cytosol Structural Constituent Of Cytoskeleton Epidermis Development Peptide Cross-linking Intermediate Filament Polymerization
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