DEUP1 and DTNB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DEUP1	DTNB
Description		deuterosome assembly protein 1	dystrobrevin beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Deuterosome	Nucleus Cytoplasm Plasma Membrane Basal Plasma Membrane Postsynaptic Density Membrane Dendrite Cell Projection Synapse Inhibitory Synapse Postsynapse
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Centriole Replication Cell Projection Organization De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation	Neuron Differentiation Synaptic Signaling
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS			A body shape index ( 34021172) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cutaneous malignant melanoma ( 32341527) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Height ( 18391951) Heschl's gyrus morphology ( 25130324) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) LDL cholesterol ( 21347282) Macular thickness ( 30535121) Multiple myeloma ( 26007630 22120009 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Nevus count or cutaneous melanoma ( 32341527) Resistant hypertension ( 31545351) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 28552196 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Working memory ( 31598132)
Interacting Genes		44 interacting genes: AMPH ARL16 BRMS1L CCDC187 CCDC85B CCHCR1 CEP57 DGCR6 DGCR6L DTNB ESRRG EXOC5 FAM50B FBF1 GEM GOLGA2 HAUS8 HGS IFIT3 ING5 KCTD9 KIFC3 KRT15 KRT28 KRT3 LNX1 NTAQ1 PIAS2 PPP1R13B RUNX1T1 SKIL SUMO1 TBC1D22B TFPT TRIM54 TXLNA TXLNB USHBP1 ZFHX3 ZNF148 ZNF460 ZNF572 ZNF655 ZNF835	61 interacting genes: ABI1 ABI2 ABI3 AMOTL2 BEGAIN CBY2 CCDC136 CCDC196 CCDC85B CCDC88B CCHCR1 CEP55 CEP63 CTBP2 DEUP1 DMD DTNBP1 FAM167A FSD2 GGA1 HMG20A KIF5A KIF5B KRT15 KRT27 KRT31 KRT33B KRT35 KRT38 KRT40 LURAP1 MB21D2 MTUS2 NDEL1 NUP62 PICK1 POU6F2 PPFIA1 PPFIBP2 PPP1R13B PRKAR1B PRTFDC1 SNCA SNTA1 SNTG1 SNTG2 SPZ1 SSBP3 TFIP11 TRAF2 TRIM27 TRIM37 TRIM54 TSACC TXLNA USHBP1 UTRN VCP VPS52 ZBTB9 ZRANB1
Entrez ID		159989	1838
HPRD ID		08689	09091
Ensembl ID		ENSG00000165325	ENSG00000138101
Uniprot IDs		E9PLX9 Q05D60	B7Z202 B7Z6A9 E7EVB6 E9PEY4 O60941 Q1I0L3
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Binding Keratin Filament	Cytoskeleton Syntrophin Complex Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Dystrophin-associated Glycoprotein Complex Cytoskeleton Organization Intermediate Filament Organization Supramolecular Fiber Organization Keratin Filament Organelle Organization Intermediate Filament Actin-based Cell Projection Protein Binding SCAR Complex Synaptic Vesicle Transport Vesicle Transport Along Microtubule Cytosol Microtubule Binding Establishment Of Vesicle Localization Sarcolemma Vesicle Cytoskeletal Trafficking Retrograde Axonal Transport Axon Cytoplasm Vesicle Localization Cytoplasm Axonal Transport Epithelial Cell Differentiation Identical Protein Binding Cytosolic Transport Microtubule-based Process Retrograde Neuronal Dense Core Vesicle Transport De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Morphogenesis Of An Epithelium Centriole Assembly Aggresome Assembly Signaling Adaptor Activity Mitotic Centrosome Separation De Novo Centriole Assembly Filopodium Axo-dendritic Transport Intracellular Transport Negative Regulation Of Cytoskeleton Organization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Organelle Transport Along Microtubule Stress Granule Disassembly Regulation Of Actin Nucleation Regulation Of Sodium Ion Transmembrane Transport Actin Binding
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